L
Louai Hauranieh
Researcher at University of California, San Francisco
Publications - 6
Citations - 117
Louai Hauranieh is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Circulating tumor cell & Metastatic breast cancer. The author has an hindex of 4, co-authored 6 publications receiving 85 citations.
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Journal ArticleDOI
Molecular Profiling of Tumor Cells in Cerebrospinal Fluid and Matched Primary Tumors from Metastatic Breast Cancer Patients with Leptomeningeal Carcinomatosis
Mark Jesus M. Magbanua,Michelle E. Melisko,Ritu Roy,Eduardo V. Sosa,Louai Hauranieh,Andrea Kablanian,Lauren E. Eisenbud,Artem Ryazantsev,Alfred Au,Janet H. Scott,John W. Park +10 more
TL;DR: The approach for isolation and molecular analysis of CSFTCs yielded new insights into the molecular nature of these cells, which may help elucidate mechanisms by which tumor cells metastasize to the central nervous system.
Journal ArticleDOI
Expanded Genomic Profiling of Circulating Tumor Cells in Metastatic Breast Cancer Patients to Assess Biomarker Status and Biology Over Time (CALGB 40502 and CALGB 40503, Alliance)
Mark Jesus M. Magbanua,Hope S. Rugo,Denise M. Wolf,Louai Hauranieh,Ritu Roy,P Pendyala,Eduardo V. Sosa,Janet H. Scott,Jin Sun Lee,Brandelyn N. Pitcher,Terry Hyslop,William T. Barry,Steven J. Isakoff,Maura N. Dickler,Laura J. van't Veer,John W. Park +15 more
TL;DR: An approach for complete isolation of EPCAM-positive CTCs and downstream comprehensive transcriptional/genomic characterization is demonstrated to examine the biology and assess breast cancer biomarkers in these cells over time.
Journal ArticleDOI
Genomic and expression profiling reveal molecular heterogeneity of disseminated tumor cells in bone marrow of early breast cancer.
Mark Jesus M. Magbanua,Hope S. Rugo,Louai Hauranieh,Ritu Roy,Janet H. Scott,Jen Chieh Lee,Feng Hsiao,Eduardo V. Sosa,Laura J. van't Veer,Laura J. Esserman,John W. Park +10 more
TL;DR: Analysis of pooled DTCs revealed molecular heterogeneity, possible genetic divergence from corresponding primary tumor, and two distinct subpopulations, both of which were different from circulating tumor cells found in the bloodstream.
Journal ArticleDOI
Genome-wide copy number analysis of cerebrospinal fluid tumor cells and their corresponding archival primary tumors.
Mark Jesus M. Magbanua,Ritu Roy,Eduardo V. Sosa,Louai Hauranieh,Andrea Kablanian,Lauren E. Eisenbud,Artem Ryazantsev,Alfred Au,Janet H. Scott,Michelle E. Melisko,John W. Park +10 more
TL;DR: This work utilized a protocol previously used for circulating tumor cell isolation to purify tumor cells from the CSF and performed genomic characterization of CSFTCs as well as archival tumors from the same patient.