L
Luc Angenot
Researcher at University of Liège
Publications - 232
Citations - 4949
Luc Angenot is an academic researcher from University of Liège. The author has contributed to research in topics: Strychnos & Loganiaceae. The author has an hindex of 38, co-authored 228 publications receiving 4570 citations. Previous affiliations of Luc Angenot include Université Paul Cézanne Aix-Marseille III.
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Journal ArticleDOI
The DNA intercalating alkaloid cryptolepine interferes with topoisomerase II and inhibits primarily DNA synthesis in B16 melanoma cells.
Karine Bonjean,M. C. De Pauw-Gillet,Marie-Paule Defresne,Pierre Colson,Claude Houssier,Laurence Dassonneville,Christian Bailly,Roland Greimers,Colin W. Wright,Joëlle Quetin-Leclercq,Mounique Tits,Luc Angenot +11 more
TL;DR: Direct evidence is provided that DNA is the primary target of cryptolepine and it is suggested that this alkaloid is a valid candidate for the development of tumor active compounds.
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About the toxicity of some Strychnos species and their alkaloids.
TL;DR: By their nature, poisons such as strychnine and curare affect the functioning of the victim's body; this also means that they have been an important source of pharmacological tools and medicines all over the world.
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Potential antimalarial activity of indole alkaloids.
TL;DR: This review covers the indole alkaloids with high antiplasmodial activity (in vitro and in vivo) isolated from natural sources, and is organized according to the different chemical structures of the alkaloid.
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Screening of medicinal plants from Reunion Island for antimalarial and cytotoxic activity
Marie-Caroline Jonville,Hippolyte Kodja,Laurence Humeau,Jacques Fournel,P. De Mol,Martine Cao,Luc Angenot,Michel Frederich +7 more
TL;DR: Two plants showed interesting antimalarial activity with good selectivity: Aphloia theiformis and Terminalia bentzoe.
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In Vitro Antiplasmodial Activity of Tithonia diversifolia and Identification of its Main Active Constituent: Tagitinin C
Eric Goffin,Eric Ziemons,Patrick De Mol,Maria do Céu Madureira,Ana Paula Martins,António Proença da Cunha,Geneviève Philippe,Monique Tits,Luc Angenot,Michel Frederich +9 more
TL;DR: The antimalarial properties of Tithonia diversifolia, an Asteraceae traditionally used to treat malaria, were investigated in vitro against three strains of Plasmodium falciparum, demonstrating good antiplasmodial activity and cytotoxic properties.