L
Luc Brunsveld
Researcher at Eindhoven University of Technology
Publications - 220
Citations - 11024
Luc Brunsveld is an academic researcher from Eindhoven University of Technology. The author has contributed to research in topics: Supramolecular chemistry & Chemistry. The author has an hindex of 49, co-authored 200 publications receiving 9528 citations. Previous affiliations of Luc Brunsveld include DSM & Max Planck Society.
Papers
More filters
Journal ArticleDOI
Structure-Activity Relationship Studies of Trisubstituted Isoxazoles as Selective Allosteric Ligands for the Retinoic-Acid-Receptor-Related Orphan Receptor γt.
Femke A. Meijer,Annet O W M Saris,Richard G. Doveston,Richard G. Doveston,Guido J.M. Oerlemans,Rens M J M de Vries,Bente A. Somsen,Anke Unger,Bert Klebl,Christian Ottmann,P.J. Cossar,Luc Brunsveld +11 more
TL;DR: In this article, the structure-activity relationship profile of the isoxazole series was explored using a combination of structure-based design, X-ray crystallography, and biochemical assays.
Journal ArticleDOI
Hydrophobicity determines the fate of self-assembled fluorescent nanoparticles in cells.
Arthur H. A. M. van Onzen,Lorenzo Albertazzi,Albertus P. H. J. Schenning,Lech-Gustav Milroy,Luc Brunsveld +4 more
TL;DR: The fate of small molecule nanoparticles composed of self-assembling intrinsically fluorescent π-conjugated oligomers was studied in cells as a function of side-chain hydrophobicity.
Journal ArticleDOI
Supramolecular Chemical Biology; Bioactive Synthetic Self-Assemblies
TL;DR: In this article, the authors highlight the diversity of self-assembled nanostructures constructed from mono-disperse synthetic building blocks, with a particular focus on their design, self-assembly, functionalization with bioactive ligands and effects thereof on the selfassembly, and possible applications.
Journal ArticleDOI
Cucurbituril-mediated immobilization of fluorescent proteins on supramolecular biomaterials
TL;DR: The reversible introduction of functionality at material surfaces is of interest for the development of functional biomaterials, and the use of supramolecular immobilization strategies facilitates mild reaction and processing conditions, as compared to other covalent analogues.
Journal ArticleDOI
Hydrophobicity directed chiral self-assembly and aggregation induced emission: Diacetylene-cored pseudopeptide chiral dopants.
TL;DR: In this article , a simple and tunable hydrophobically driven chiral functional assembly of diacetylene cored pseudopeptides is described. But the core of the dialkyne can be adjusted by tuning the solvent environment, with for example self-assembly into vesicles in acetonitrile and into helical organization with AIE in a H 2 O/DMSO mixture.