THE DESIGN AND ANALYSIS OF EXPERIMENTS. By Oscar Kempthorne. New York, John Wiley and Sons, Inc., 1952. 631 pp. $8.50. This book by a teacher of statistics (as well as a consultant for \"experimenters\") is a comprehensive study of the philosophical background for the statistical design of experiment. It is necessary to have some facility with algebraic notation and manipulation to be able to use the volume intelligently. The problems are presented from the theoretical point of view, without such practical examples as would be helpful for those not acquainted with mathematics. The mathematical justification for the techniques is given. As a somewhat advanced treatment of the design and analysis of experiments, this volume will be interesting and helpful for many who approach statistics theoretically as well as practically. With emphasis on the \"why,\" and with description given broadly, the author relates the subject matter to the general theory of statistics and to the general problem of experimental inference. MARGARET J. ROBERTSON

The Design and Analysis of Experiments

Statistics for Spatial Data.

http://ee.sharif.edu/~miap/Files/A%20Survey%20of%20Medical%20Image%20Registration.pdf

A survey of medical image registration.

The successful application of a conceptual rainfall-runoff (CRR) model depends on how well it is calibrated. Despite the popularity of CRR models, reports in the literature indicate that it is typically difficult, if not impossible, to obtain unique optimal values for their parameters using automatic calibration methods. Unless the best set of parameters associated with a given calibration data set can be found, it is difficult to determine how sensitive the parameter estimates (and hence the model forecasts) are to factors such as input and output data error, model error, quantity and quality of data, objective function used, and so on. Results are presented that establish clearly the nature of the multiple optima problem for the research CRR model SIXPAR. These results suggest that the CRR model optimization problem is more difficult than had been previously thought and that currently used local search procedures have a very low probability of successfully finding the optimal parameter sets. Next, the performance of three existing global search procedures are evaluated on the model SIXPAR. Finally, a powerful new global optimization procedure is presented, entitled the shuffled complex evolution (SCE-UA) method, which was able to consistently locate the global optimum of the SIXPAR model, and appears to be capable of efficiently and effectively solving the CRR model optimization problem.

Effective and efficient global optimization for conceptual rainfall‐runoff models

We present an automatic subpixel registration algorithm that minimizes the mean square intensity difference between a reference and a test data set, which can be either images (two-dimensional) or volumes (three-dimensional). It uses an explicit spline representation of the images in conjunction with spline processing, and is based on a coarse-to-fine iterative strategy (pyramid approach). The minimization is performed according to a new variation (ML*) of the Marquardt-Levenberg algorithm for nonlinear least-square optimization. The geometric deformation model is a global three-dimensional (3-D) affine transformation that can be optionally restricted to rigid-body motion (rotation and translation), combined with isometric scaling. It also includes an optional adjustment of image contrast differences. We obtain excellent results for the registration of intramodality positron emission tomography (PET) and functional magnetic resonance imaging (fMRI) data. We conclude that the multiresolution refinement strategy is more robust than a comparable single-stage method, being less likely to be trapped into a false local optimum. In addition, our improved version of the Marquardt-Levenberg algorithm is faster.

/pdf/a-pyramid-approach-to-subpixel-registration-based-on-41xhw0es6x.pdf

A pyramid approach to subpixel registration based on intensity

Identification of parametric models : from experimental data

When setting up a computer experiment, it has become a standard practice to select the inputs spread out uniformly across the available space. These so-called space-filling designs are now ubiquitous in corresponding publications and conferences. The statistical folklore is that such designs have superior properties when it comes to prediction and estimation of emulator functions. In this paper we want to review the circumstances under which this superiority holds, provide some new arguments and clarify the motives to go beyond space-filling. An overview over the state of the art of space-filling is introducing and complementing these results.

/pdf/design-of-computer-experiments-space-filling-and-beyond-4spwcdrcy3.pdf

Design of computer experiments: space filling and beyond

Qualitative and quantitative experiment design for phenomenological models—a survey

A class of estimators of the Renyi and Tsallis entropies of an unknown distribution f in R^m is presented. These estimators are based on the k-th nearest-neighbor distances computed from a sample of N i.i.d. vectors with distribution f. We show that entropies of any order q, including Shannon's entropy, can be estimated consistently with minimal assumptions on f. Moreover, we show that it is straightforward to extend the nearest-neighbor method to estimate the statistical distance between two distributions using one i.i.d. sample from each.

/pdf/a-class-of-renyi-information-estimators-for-multidimensional-2snwur3ozs.pdf

A class of Rényi information estimators for multidimensional densities

https://hal.archives-ouvertes.fr/hal-00259532/document

Luc Pronzato

Papers

Identification of parametric models : from experimental data

Design of computer experiments: space filling and beyond

Qualitative and quantitative experiment design for phenomenological models—a survey

A class of Rényi information estimators for multidimensional densities

Survey paper: Optimal experimental design and some related control problems