Lucas G. Nivón

TL;DR: Because nanopores can rapidly discriminate and characterize unlabeled DNA molecules at low copy number, refinements of the experimental approach demonstrated here could eventually provide a low-cost high-throughput method of analyzing DNA polynucleotides.

TL;DR: Current blockade and time distributions for single-stranded DNA polymers during voltage-driven translocations through a single alpha-hemolysin pore imply that, while polymers longer than the pore are translocated at a constant speed, the velocity of shorter polymers increases with decreasing length.

TL;DR: The effects of chronic stress on hippocampal physiology and long‐term potentiation (LTP) in the CA3 and dentate gyrus suggest that chronic stress produces changes in the input‐output relationship in the hippocampal trisynaptic circuit which could affect information flow through this structure.

TL;DR: Because the five newly determined PrPC structures originate from species with widely different transmissible spongiform encephalopathy records, the present data indicate previously uncharacterized possible correlations between local features in PrPC three-dimensional structures and susceptibility of different mammalian species to transmissible scrofa encephalopathies.

TL;DR: A protocol using cycles of minimization with combined backbone/sidechain restraints that is Pareto-optimal with respect to RMSD to the native structure and energetic strain reduction is described.