L
Lucian Mihai Itu
Researcher at Siemens
Publications - 114
Citations - 1720
Lucian Mihai Itu is an academic researcher from Siemens. The author has contributed to research in topics: Fractional flow reserve & Deep learning. The author has an hindex of 19, co-authored 97 publications receiving 1383 citations. Previous affiliations of Lucian Mihai Itu include Transilvania University of Brașov & Princeton University.
Papers
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Journal ArticleDOI
Comparison of Fractional Flow Reserve Based on Computational Fluid Dynamics Modeling Using Coronary Angiographic Vessel Morphology Versus Invasively Measured Fractional Flow Reserve
Monique Tröbs,Stephan Achenbach,Jens Röther,Thomas Redel,Michael Scheuering,David Winneberger,Klaus Klingenbeck,Lucian Mihai Itu,Tiziano Passerini,Ali Kamen,Puneet Sharma,Dorin Comaniciu,Christian Schlundt +12 more
TL;DR: Estimation of coronary FFR with PC-based computational fluid dynamics modeling on the basis of lesion morphology as determined by invasive angiography is possible with high diagnostic accuracy compared to invasive measurements.
Journal ArticleDOI
Non-Invasive Hemodynamic Assessment of Aortic Coarctation: Validation with In Vivo Measurements
Lucian Mihai Itu,Lucian Mihai Itu,Puneet Sharma,Kristof Ralovich,Kristof Ralovich,Viorel Mihalef,Razvan Ioan Ionasec,Allen D. Everett,Richard Ringel,Ali Kamen,Dorin Comaniciu +10 more
TL;DR: The preliminary results are promising, with a mean absolute error of less than 2 mmHg in all the patients, and the proposed CFD-based algorithm is fully automatic, requiring no iterative tuning procedures for matching the computed results to observed patient data, thus making it feasible for use in a clinical setting.
Proceedings ArticleDOI
A patient-specific reduced-order model for coronary circulation
TL;DR: A patient-specific model for coronary circulation is introduced, by combining anatomical, hemodynamic and functional information from medical images and other clinical observations, to provide a model for virtual assessment of the flow and underlying functional measures in healthy and stenosed coronary arteries.
Proceedings ArticleDOI
A framework for personalization of coronary flow computations during rest and hyperemia
Puneet Sharma,Lucian Mihai Itu,Xudong Zheng,Ali Kamen,Dominik Bernhardt,Constantin Suciu,Dorin Comaniciu +6 more
TL;DR: A CFD based method for performing patient-specific coronary hemodynamic computations under two conditions: at rest and during drug-induced hyperemia, demonstrating that the estimation of the hyperemic resistances is crucial to obtain accurate values for pressure and flow rates.
Journal ArticleDOI
Coronary CT angiography derived fractional flow reserve: Methodology and evaluation of a point of care algorithm.
Adriaan Coenen,Marisa Lubbers,Akira Kurata,Atsushi K. Kono,Admir Dedic,Raluca G. Chelu,Marcel L. Dijkshoorn,Robert-Jan van Geuns,Max Schoebinger,Lucian Mihai Itu,Puneet Sharma,Koen Nieman +11 more
TL;DR: On-site calculation of CTA-FFR can identify hemodynamically significant CAD with an overall per-vessel accuracy of 75% in comparison to invasive FFR, and is negatively affected by misalignment artifacts.