L
Ludovic C Gillet
Researcher at ETH Zurich
Publications - 49
Citations - 7857
Ludovic C Gillet is an academic researcher from ETH Zurich. The author has contributed to research in topics: Proteome & Gene. The author has an hindex of 26, co-authored 44 publications receiving 6363 citations. Previous affiliations of Ludovic C Gillet include Novartis & University of Zurich.
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Journal ArticleDOI
Targeted Data Extraction of the MS/MS Spectra Generated by Data-independent Acquisition: A New Concept for Consistent and Accurate Proteome Analysis
Ludovic C Gillet,Pedro Navarro,Stephen Tate,Hannes L. Röst,Nathalie Selevsek,Lukas Reiter,Ron Bonner,Ruedi Aebersold,Ruedi Aebersold +8 more
TL;DR: A new strategy that systematically queries sample sets for the presence and quantity of essentially any protein of interest is presented, using the information available in fragment ion spectral libraries to mine the complete fragment ion maps generated using a data-independent acquisition method.
Journal ArticleDOI
OpenSWATH enables automated, targeted analysis of data-independent acquisition MS data
Hannes L. Röst,George Rosenberger,Pedro Navarro,Ludovic C Gillet,Saša M. Miladinović,Olga T. Schubert,Witold Wolski,Ben C. Collins,Johan Malmström,Lars Malmström,Ruedi Aebersold +10 more
TL;DR: This research presents a novel and scalable approaches that allow for real-time measurement of the response of the immune system to treatments such as chemotherapy and immunotherapy.
Journal ArticleDOI
Data‐independent acquisition‐based SWATH ‐ MS for quantitative proteomics: a tutorial
Christina Ludwig,Ludovic C Gillet,George Rosenberger,George Rosenberger,Sabine Amon,Ben C. Collins,Ruedi Aebersold,Ruedi Aebersold +7 more
TL;DR: This tutorial provides guidelines on how to set up and plan a SWATH‐MS experiment, how to perform the mass spectrometric measurement and how to analyse SWath‐MS data using peptide‐centric scoring.
Journal ArticleDOI
Molecular mechanisms of mammalian global genome nucleotide excision repair.
Journal ArticleDOI
Rapid mass spectrometric conversion of tissue biopsy samples into permanent quantitative digital proteome maps
Tiannan Guo,Petri Kouvonen,Ching Chiek Koh,Ludovic C Gillet,Witold Wolski,Hannes L. Röst,George Rosenberger,George Rosenberger,Ben C. Collins,Lorenz C. Blum,Silke Gillessen,Markus Joerger,Wolfram Jochum,Ruedi Aebersold +13 more
TL;DR: This work uses a fast and reproducible conversion of a small amount of tissue into a single, permanent digital file representing the mass spectrometry (MS)-measurable proteome of the sample to process and convert 18 biopsy samples from nine patients with renal cell carcinoma into SWATH-MS fragment ion maps.