L
Luis H. F. Do Vale
Researcher at Northwestern University
Publications - 11
Citations - 348
Luis H. F. Do Vale is an academic researcher from Northwestern University. The author has contributed to research in topics: Chemistry & Trichoderma harzianum. The author has an hindex of 8, co-authored 9 publications receiving 295 citations. Previous affiliations of Luis H. F. Do Vale include University of Brasília.
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Journal ArticleDOI
Top-down characterization of endogenous protein complexes with native proteomics.
Owen S. Skinner,Nicole A. Haverland,Luca Fornelli,Rafael D. Melani,Luis H. F. Do Vale,Luis H. F. Do Vale,Henrique S. Seckler,Peter F. Doubleday,Luis F. Schachner,Kristina Srzentić,Neil L. Kelleher,Philip D. Compton +11 more
TL;DR: In this article, a multistage tandem MS approach was used to characterize 125 intact endogenous complexes and 217 distinct proteoforms derived from mouse heart and human cancer cell lines in discovery mode.
Journal ArticleDOI
An informatic framework for decoding protein complexes by top-down mass spectrometry
Owen S. Skinner,Pierre C. Havugimana,Nicole A. Haverland,Luca Fornelli,Bryan P. Early,Joseph B. Greer,Ryan T. Fellers,Kenneth R. Durbin,Luis H. F. Do Vale,Luis H. F. Do Vale,Rafael D. Melani,Henrique S. Seckler,Micah T. Nelp,Mikhail E. Belov,Stevan Horning,Alexander Makarov,Richard D. LeDuc,Vahe Bandarian,Philip D. Compton,Neil L. Kelleher +19 more
TL;DR: A computational search strategy is reported that supports hierarchical top-down analysis for precise identification and scoring of multi-proteoform complexes by native mass spectrometry.
Journal ArticleDOI
Secretome analysis of the fungus Trichoderma harzianum grown on cellulose
Luis H. F. Do Vale,Diana Paola Gómez-Mendoza,Min-Sik Kim,Akhilesh Pandey,Carlos André Ornelas Ricart,Ximenes F.Filho Edivaldo,Marcelo Valle de Sousa +6 more
TL;DR: The extensive secretome analysis of T. harzianum highlights the importance of this fungus as a rich source of hydrolytic enzymes for bioconversion and biocontrol applications.
Journal ArticleDOI
Native GELFrEE: a new separation technique for biomolecular assemblies.
Owen S. Skinner,Luis H. F. Do Vale,Luis H. F. Do Vale,Adam D. Catherman,Pierre C. Havugimana,Marcelo Valle de Sousa,Philip D. Compton,Neil L. Kelleher +7 more
TL;DR: This work detail and optimize the use of tube gel separations to produce samples proven compatible with native, multistage mass spectrometry (nMS/MS) and offers the prospect of untargeted proteomics at the next hierarchical level of protein organization in biology.
Journal ArticleDOI
Secretomic survey of Trichoderma harzianum grown on plant biomass substrates.
Diana Paola Gómez-Mendoza,Magno Junqueira,Luis H. F. Do Vale,Gilberto B. Domont,Edivaldo Ximenes Ferreira Filho,Marcelo Valle de Sousa,Carlos André Ornelas Ricart +6 more
TL;DR: The results showed that SB induced the highest cellulolytic and xylanolytic activities when compared with the other substrates, while remarkable differences in terms of number and distribution of protein spots in 2-DE gels were observed among the samples.