Luisa De Risio

TL;DR: Among prefrontal regions, orbital and ventromedial areas seem to be a possible nexus for sensory integration, value‐based decision‐making and emotional processing, thus contributing to both motivational and affective aspects of cognitive control.

TL;DR: High levels of impulsivity and craving for alcohol seem to be associated with other addictive behaviors, and a significant rate of co-occurrence of BAs in AUD is emphasized.

TL;DR: A model for PG (incorporating anhedonia, impulsivity levels and frontal impairment) is discussed in the context of the pathophysiology of addictive behaviors, suggesting the impairment of hedonic capacity might facilitate loss of control over reward-related behavior, thus favoring the shift towards predominantly habit-based compulsive behaviors.

TL;DR: The major finding of this study is that euthymic bipolar patients and remitted major depressed patients display residual anhedonic symptoms, suggesting that, in affective disorder patients, altered hedonic capacity could represent an enduring trait and that, possibly, dysfunctions in the neurobiological mechanisms underlying hedonics response and reward processing persist, irrespective of mood state.

TL;DR: Overall, results show a largely beneficial effect of active rTMS compared to sham stimulation, as reflected in the statistically significant recovery of both helplessness and anhedonic profiles.