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Lun Cai

Researcher at Chinese Academy of Sciences

Publications -  11
Citations -  1339

Lun Cai is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Gene & Non-coding RNA. The author has an hindex of 8, co-authored 11 publications receiving 1248 citations.

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Topological structure analysis of the protein–protein interaction network in budding yeast

TL;DR: A spectral method derived from graph theory was introduced to uncover hidden topological structures (i.e. quasi-cliques and quasi-bipartites) of complicated protein-protein interaction networks and suggest that they consist of biologically relevant functional groups.
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NONCODE: an integrated knowledge database of non-coding RNAs

TL;DR: A novel classification system, labeled process function class, to integrate existing classification systems and provides a user-friendly interface, a visualization platform and a convenient search option, allowing efficient recovery of sequence, regulatory elements in the flanking sequences, secondary structure, related publications and other information.
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Organization of the Caenorhabditis elegans small non-coding transcriptome: genomic features, biogenesis, and expression.

TL;DR: Two new classes of ncRNAs are identified, stem-bulge RNAs (sbRNAs) and snRNA-likeRNAs (snlRNAs), both featuring distinct internal motifs, secondary structures, upstream elements, and high and developmentally variable expression.
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The interactome as a tree--an attempt to visualize the protein-protein interaction network in yeast.

TL;DR: Compared with previous clustering methods, the clustering method ADJW performs well both in retaining a meaningful image of the protein interaction network as well as in enriching the image with biological information, therefore is more suitable in visualization of the network.
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Profiling Caenorhabditis elegans non-coding RNA expression with a combined microarray

TL;DR: The microarray analysis presents a more complete and detailed picture of a non-coding transcriptome of Caenorhabditis elegans than hitherto has been presented for any other multicellular organism.