L
Lun Cai
Researcher at Chinese Academy of Sciences
Publications - 11
Citations - 1339
Lun Cai is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Gene & Non-coding RNA. The author has an hindex of 8, co-authored 11 publications receiving 1248 citations.
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Journal ArticleDOI
Topological structure analysis of the protein–protein interaction network in budding yeast
Dongbo Bu,Yi Zhao,Lun Cai,Hong Xue,Xiaopeng Zhu,Hongchao Lu,Jingfen Zhang,Shiwei Sun,Lunjiang Ling,Nan Zhang,Guojie Li,Runsheng Chen +11 more
TL;DR: A spectral method derived from graph theory was introduced to uncover hidden topological structures (i.e. quasi-cliques and quasi-bipartites) of complicated protein-protein interaction networks and suggest that they consist of biologically relevant functional groups.
Journal ArticleDOI
NONCODE: an integrated knowledge database of non-coding RNAs
Changning Liu,Baoyan Bai,Geir Skogerbø,Lun Cai,Wei Deng,Yong Zhang,Dongbo Bu,Yi-Pei Zhao,Runsheng Chen +8 more
TL;DR: A novel classification system, labeled process function class, to integrate existing classification systems and provides a user-friendly interface, a visualization platform and a convenient search option, allowing efficient recovery of sequence, regulatory elements in the flanking sequences, secondary structure, related publications and other information.
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Organization of the Caenorhabditis elegans small non-coding transcriptome: genomic features, biogenesis, and expression.
Wei Deng,Xiaopeng Zhu,Geir Skogerbø,Yi Zhao,Zhuo Fu,Yudong Wang,Housheng He,Lun Cai,Hong Sun,Changning Liu,Biao Li,Biao Li,Baoyan Bai,Jie Wang,Dong Jia,Shiwei Sun,Hang He,Yan Cui,Yu Wang,Dongbo Bu,Runsheng Chen +20 more
TL;DR: Two new classes of ncRNAs are identified, stem-bulge RNAs (sbRNAs) and snRNA-likeRNAs (snlRNAs), both featuring distinct internal motifs, secondary structures, upstream elements, and high and developmentally variable expression.
Journal ArticleDOI
The interactome as a tree--an attempt to visualize the protein-protein interaction network in yeast.
Hongchao Lu,Xiaopeng Zhu,Haifeng Liu,Geir Skogerbø,Jingfen Zhang,Yong Zhang,Lun Cai,Yi Zhao,Shiwei Sun,Jingyi Xu,Dongbo Bu,Runsheng Chen +11 more
TL;DR: Compared with previous clustering methods, the clustering method ADJW performs well both in retaining a meaningful image of the protein interaction network as well as in enriching the image with biological information, therefore is more suitable in visualization of the network.
Journal ArticleDOI
Profiling Caenorhabditis elegans non-coding RNA expression with a combined microarray
Housheng H. He,Lun Cai,Geir Skogerbø,Wei Deng,Tao Liu,Xiaopeng Zhu,Yudong Wang,Dong Jia,Zhihua Zhang,Yong-Chuan Tao,Haipan Zeng,Muhammad Aftab,Yan-Yan Cui,Guozhen Liu,Runsheng Chen +14 more
TL;DR: The microarray analysis presents a more complete and detailed picture of a non-coding transcriptome of Caenorhabditis elegans than hitherto has been presented for any other multicellular organism.