Luodan Yu

TL;DR: This work not only demonstrates the promising clinical application potentials of BG@NbSiR scaffold‐based therapy against bone metastasis of breast cancer, but also provides distinctive avenues to optimize the design and construction of multifunctional tissue‐engineering biomaterials based on single‐cell genomes.

TL;DR: A distinct TiO2Fe3O4@PEG Janus nanostructure is rationally designed and engineered for bilaterally enhanced SDT and chemodynamic therapy (CDT), which can both accelerate mass transfer and chemical reaction rates of the Fenton reaction to enhance the CDT effect.

TL;DR: A nanosonosensitizer (PpIX)-based liposomal nanosystem is constructed, which simultaneously encapsulated clinically approved iron supplement ferumoxytol, for inducing dual ferroptosis/apoptosis pathways by SDT-based oxidative ferrotherapy.

TL;DR: Enhanced anticancer efficiency of chemotherapeutic drugs assisted by the biodegradable intelligent HMMSNs is achieved and can be easily excreted via feces and urine guaranteeing their further clinical translation.

TL;DR: In this paper, the intrinsic chemistry (e.g., material chemistry, surface chemistry, physiochemistry and biochemistry) and design principle of versatile nanosystems/nanoplatforms with unique ultrasound response not only for diagnostic bioimaging (single and/or multi-modality ultrasound imaging), but also for multiple ultrasound-triggered therapeutic applications.