L
Lusânia Maria Greggi Antunes
Researcher at University of São Paulo
Publications - 133
Citations - 4326
Lusânia Maria Greggi Antunes is an academic researcher from University of São Paulo. The author has contributed to research in topics: Genotoxicity & Comet assay. The author has an hindex of 32, co-authored 128 publications receiving 3814 citations.
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Genotoxic studies in hypertensive and normotensive rats treated with amiodarone
Mara Ribeiro Almeida,Estela de Oliveira Lima,Valdo José Dias da Silva,Mateus Gandra Campos,Lusânia Maria Greggi Antunes,A. K. Salman,Francisca da Luz Dias +6 more
TL;DR: Treatment with amiodarone was genotoxic in WKYs, but not in SHRs, a well-characterized model for hypertension, and further studies are needed to confirm whether amioarone is genot toxic or efficient and harmless, among humans undergoing therapy.
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Effects of maternal vitamin B6 deficiency and over-supplementation on DNA damage and oxidative stress in rat dams and their offspring
Mara Ribeiro Almeida,Vinícius de Paula Venâncio,Alexandre Ferro Aissa,Joana D'Arc Castania Darin,Maria de Lourdes Pires Bianchi,Lusânia Maria Greggi Antunes +5 more
TL;DR: It is found that maternal vitamin B6 deficiency increased the micronucleus frequency in peripheral blood and bone marrow cells and also increased the concentration of hepatic TBARS (thiobarbituric acid reactive substances) in newborn pups (10 days old).
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Effects of lutein and chlorophyll b on GSH depletion and DNA damage induced by cisplatin in vivo
Juliana Mara Serpeloni,Mara Ribeiro Almeida,Adriana Zerlotti Mercadante,Maria de Lourdes Pires Bianchi,Lusânia Maria Greggi Antunes +4 more
TL;DR: Results show that the combination of LT and CLb, which are both usually present in the same foods, such as leafy green vegetables, can be used safely and is likely related to antioxidant properties in peripheral blood cells through the prevention of cDDP-induced GSH depletion.
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Differential genotoxicity and cytotoxicity of phomoxanthone A isolated from the fungus Phomopsis longicolla in HL60 cells and peripheral blood lymphocytes.
Gabriel Brolio Pavão,Vinícius de Paula Venâncio,Ana Ligia Leandrini de Oliveira,Lívia Cristina Hernandes,Mara Ribeiro Almeida,Lusânia Maria Greggi Antunes,Hosana Maria Debonsi +6 more
TL;DR: PhoA was highly selective towards HL60 compared to lymphocytes, causing no damage in the latter cell line, suggesting that this compound could be a promising compound in antitumoral drug development.
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Olive oil protects against chromosomal aberrations induced by doxorubicin in wistar rat bone marrow cells
TL;DR: Rat bone marrow cells treated simultaneously with olive oil and Doxorubicin developed significantly fewer chromosomal aberrations and abnormal metaphases than those treated with DXR alone.