L
Lusânia Maria Greggi Antunes
Researcher at University of São Paulo
Publications - 133
Citations - 4326
Lusânia Maria Greggi Antunes is an academic researcher from University of São Paulo. The author has contributed to research in topics: Genotoxicity & Comet assay. The author has an hindex of 32, co-authored 128 publications receiving 3814 citations.
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Journal ArticleDOI
Effects of selenium pretreatment on cisplatin-induced chromosome aberrations in wistar rats.
Lusânia Maria Greggi Antunes,Heloísa Della Coletta Francescato,Joana D'Arc Castania Darin,Maria de Lourdes Pires Bianchi +3 more
TL;DR: No protective response was obtained with either a single or double dose of selenium in rats treated with cisplatin, and the combination between seenium+vitamin C was no more effective than vitamin C alone in the protection against damage caused by this antitumor drug.
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Coenzyme Q10 and its effects in the treatment of neurodegenerative diseases
Graciela Cristina dos Santos,Lusânia Maria Greggi Antunes,Antonio Cardozo dos Santos,Maria de Lourdes Pires Bianchi +3 more
TL;DR: In several animal models of neurodegenerative diseases, Co Q10 has shown beneficial effects in reducing disease progression, however, further studies are needed to assess the outcome and effectiveness of CoQ10 before exposing patients to unnecessary health risks at significant costs.
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Maternal vitamin B6 deficient or supplemented diets on expression of genes related to GABAergic, serotonergic, or glutamatergic pathways in hippocampus of rat dams and their offspring.
Mara Ribeiro Almeida,Mara Ribeiro Almeida,Lawrence Mabasa,Courtney Crane,Chung S. Park,Vinícius de Paula Venâncio,Maria de Lourdes Pires Bianchi,Lusânia Maria Greggi Antunes +7 more
TL;DR: A maternal vitamin B6 -deficient diet affects the expression of genes related to GABA, glutamate, and serotonin metabolisms in offspring by regulating Gad1, Glul, Gls, and Tph1 mRNA expression.
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Adaptive epigenetic response of glutathione (GSH)-related genes against lead (Pb)-induced toxicity, in individuals chronically exposed to the metal.
Paula Pícoli Devóz,Mariana Bisarro dos Reis,Willian Robert Gomes,Flora Troina Maraslis,Diego Luis Ribeiro,Lusânia Maria Greggi Antunes,Bruno Lemos Batista,Denise Grotto,Rui Manuel Reis,Fernando Barbosa,Gustavo Rafael Mazzaron Barcelos +10 more
TL;DR: Assessment of Pb exposure on methylation of GSH-related genes' promoter regions and their influence on biomarkers of oxidative stress, in workers exposed to the metal gives further evidence about adaptive epigenetic response to avoid oxidative damage induced by Pb Exposure.
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Cytogenetic biomonitoring of inhabitants of a large uranium mineralization area: the municipalities of Monte Alegre, Prainha, and Alenquer, in the State of Pará, Brazil
Adriana Costa Guimarães,Lusânia Maria Greggi Antunes,Helem Ferreira Ribeiro,Ândrea Kelly Ribeiro dos Santos,Plínio Cerqueira dos Santos Cardoso,Patrícia Lima de Lima,Aline Damasceno Seabra,Thaís Brilhante Pontes,Cláudia Pessoa,Manoel Odorico de Moraes,Bruno C. Cavalcanti,Carla Maria Lima Sombra,Marcelo de Oliveira Bahia,Rommel Rodríguez Burbano +13 more
TL;DR: Genetic analyses suggest that the radiation in the study area is not high enough to induce DNA alterations or to interfere with mitotic apparatus formation, and it is also possible that damages caused by radiation doses undergo cellular repair.