Lyle J. Graham

TL;DR: This intracellular study investigates synaptic mechanisms of orientation and direction selectivity in cat area 17 by detecting spike suppression, hyperpolarization, and reduction of trial-to-trial variability of membrane potential and concludes that excitatory and inhibitory inputs share the tuning preference of spiking output.

TL;DR: The persistent Na+ current, INaP, is known to amplify subthreshold oscillations and synaptic potentials, but its impact on action potential generation remains enigmatic, and model simulations demonstrated that I(NaP) increased the relative refractory period and decreased interspike-interval variability under conditions resembling an active network in vivo.

TL;DR: Using simultaneous whole-cell recordings from soma and apical dendrites from rat CA1 hippocampal pyramidal cells, and biophysically detailed modeling, two complementary resonance (bandpass) filters of subthreshold voltage signals are found that convey voltage-dependent tuning of theta-mediated neural coding in the entorhinal/hippocampal system during locomotion, spatial navigation, memory, and sleep.

TL;DR: The expected firing probability of a stochastic neuron is approximated by a function of the expected subthreshold membrane potential, for the case of colored noise, in order to extend the recently proposed white noise model to conductance-based neurons.

TL;DR: How stochasticity of ion channels may influence spike timing and thus coding for neurons with functionally localized concentrations of channels, such as in "hot spots" of dendrites, spines or axons is suggested.