M
M A Gayle
Researcher at Amgen
Publications - 1
Citations - 625
M A Gayle is an academic researcher from Amgen. The author has contributed to research in topics: Interleukin 1 receptor, type I & Interleukin-21 receptor. The author has an hindex of 1, co-authored 1 publications receiving 619 citations.
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Journal ArticleDOI
Interleukin 1 signaling occurs exclusively via the type I receptor.
John E. Sims,M A Gayle,Jennifer L. Slack,Mark R. Alderson,T A Bird,J G Giri,Francesco Colotta,Fabio Re,Alberto Mantovani,K Shanebeck +9 more
TL;DR: It is concluded that a very small number of type I receptors is sufficient to mediate all of the actions of IL-1 which are examined here and that the function of the type II receptor may not be to transduce signals.