M
M. A. Ghatei
Researcher at Imperial College London
Publications - 410
Citations - 37476
M. A. Ghatei is an academic researcher from Imperial College London. The author has contributed to research in topics: Enteroglucagon & Calcitonin gene-related peptide. The author has an hindex of 90, co-authored 410 publications receiving 36233 citations. Previous affiliations of M. A. Ghatei include Bristol Royal Infirmary & Hammersmith Hospital.
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Journal ArticleDOI
Exogenous peptide YY3-36 and Exendin-4 further decrease food intake, whereas octreotide increases food intake in rats after Roux-en-Y gastric bypass
Wiebke Fenske,Marco Bueter,Marco Bueter,Alexander D. Miras,M. A. Ghatei,S.R. Bloom,C. W. le Roux +6 more
TL;DR: The endogenous gut hormone response after gastric bypass can thus potentially be further enhanced by additional exogenous therapy with pharmacological doses of gut hormones in patients with insufficient weight loss or weight regain after surgery.
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Expression of the C-terminal peptide of human pro-bombesin in 361 lung endocrine tumours, a reliable marker and possible prognostic indicator for small cell carcinoma
Q. Hamid,B. J. Addis,David R. Springall,Nassif B.N. Ibrahim,M. A. Ghatei,S.R. Bloom,J.M. Polak +6 more
TL;DR: The apparent presence of the C-terminal peptide of human pro-bombesin in higher concentrations than bombsin in the more malignant class of endocrine tumours, mainly small cell carcinomas associated with the poorest prognosis, suggests that the antiserum to this C- terminal peptide may prove to be of value in investigating the biological behaviour of smallcell carcinomas and predicting the clinical course of the disease.
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Production of endothelin by vascular smooth muscle cells
TL;DR: The low level production of ET-1 by vascular smooth muscle cells may have an important autocrine function and may be under regulation of neuropeptides localized to perivascular nerves.
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Subcutaneous oxyntomodulin analogue administration reduces body weight in lean and obese rodents
Y. L. Liu,H. E. Ford,Maralyn Druce,Maralyn Druce,James Minnion,Benjamin C. T. Field,J. C. Shillito,J. Baxter,Kevin Murphy,M. A. Ghatei,S.R. Bloom +10 more
TL;DR: OXM6421 induces negative energy balance in both lean and obese rodents, suggesting that long-acting OXM analogues may represent a potential therapy for obesity.
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Depletion of neuropeptides during wound healing in rat skin.
TL;DR: A significant depletion of the neuropeptides was found in the region of the wound within two days, and this persisted for two weeks, and a smaller and delayed depletion also occurred in intact skin of the same dermatome, but not in an adjacent dermatome.