M
M.A. von Wronski
Publications - 1
Citations - 57
M.A. von Wronski is an academic researcher. The author has contributed to research in topics: Receptor tyrosine kinase & Ligand (biochemistry). The author has an hindex of 1, co-authored 1 publications receiving 54 citations.
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A distinct strategy to generate high-affinity peptide binders to receptor tyrosine kinases
A. Shrivastava,M.A. von Wronski,Aaron K. Sato,Daniel T. Dransfield,Daniel J. Sexton,Nancy J. Bogdan,Radhakrishna Pillai,P. Nanjappan,Bo Song,E. Marinelli,Daniel B. DeOliveira,C. Luneau,Mary Devlin,A. Muruganandam,A. Abujoub,G. Connelly,Q.L. Wu,Greg Conley,Q. Chang,Michael F. Tweedle,Robert C. Ladner,Rolf E Swenson,Adrian D. Nunn +22 more
TL;DR: A novel and general way of generating high affinity peptide (HAP) binders to receptor tyrosine kinases (RTKs) using a multi-step process comprising phage-display selection, identification of peptide pairs suitable for hetero-dimerization and chemical synthesis of heterodimers is described.