M
M.C. Pike
Researcher at University of Oxford
Publications - 21
Citations - 14184
M.C. Pike is an academic researcher from University of Oxford. The author has contributed to research in topics: Cancer & Estrogen. The author has an hindex of 17, co-authored 21 publications receiving 14032 citations. Previous affiliations of M.C. Pike include University of Southern California.
Papers
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Journal ArticleDOI
Estrogens and Endometrial Cancer in a Retirement Community
Thomas M. Mack,M.C. Pike,Brian E. Henderson,Robert I. Pfeffer,Vibeke R. Gerkins,Mary Arthur,Sandra E. Brown +6 more
TL;DR: For an estrogen user, the risk from endometrial cancer appeared to exceed by far the base-line risk from any other single cancer, and a dose-response effect was demonstrated.
Journal ArticleDOI
Do regular ovulatory cycles increase breast cancer risk
TL;DR: The “estrogen window hypothesis” of the etiology of breast cancer proposes that unopposed estrogen stimulation is the most favorable state for tumor induction and that normal postovulation progesterone secretion reduces susceptibility.
Journal ArticleDOI
Estrogen-Progestin Replacement Therapy and Endometrial Cancer
M.C. Pike,Ruth K. Peters,Wendy Cozen,Nicole Probst-Hensch,Juan C. Felix,Peggy Wan,Thomas M. Mack +6 more
TL;DR: The progestin in sequential estrogen‐progestin replacement therapy needs to be given for at least 10 days to block effectively any increased risk of endometrial cancer.
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Hormonal chemoprevention of cancer in women
TL;DR: Although the incidence of breast cancer has not been substantially affected by current oral contraceptives, it may be possible to develop alternative forms of contraception that provide protection against all three cancers.
Journal ArticleDOI
Age-related factors in cancers of the breast, ovary, and endometrium.
TL;DR: Different "models" are constructed for each of these three tumour sites and shown to provide an excellent description of most of the known epidemiology of each of the cancers, and to provide a basis for predicting the long-term effects of various factors on the risk of these diseases.