https://aasldpubs.onlinelibrary.wiley.com/doi/epdf/10.1053/jhep.2003.50346

A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C

https://aasldpubs.onlinelibrary.wiley.com/doi/epdf/10.1002/hep.21178

Development of a simple noninvasive index to predict significant fibrosis in patients with HIV/HCV coinfection

ISOLATED ALTERATIONS OF BIOCHEMICAL MARKERS OF LIVER DAMAGE in a seemingly healthy patient can present a challenge for the clinician. In this review we provide a guide to interpreting alterations to liver enzyme levels. The functional anatomy of the liver and pathophysiology of liver enzyme alteration are briefly reviewed. Using a schematic approach that classifies enzyme alterations as predominantly hepatocellular or predominantly cholestatic, we review abnormal enzymatic activity within the 2 subgroups, the most common causes of enzyme alteration and suggested initial investigations.

/pdf/liver-enzyme-alteration-a-guide-for-clinicians-jxz9dbq4z2.pdf

Liver enzyme alteration: a guide for clinicians

Evaluation of liver fibrosis: a concise review.

AST/ALT ratio predicts cirrhosis in patients with chronic hepatitis C virus infection.

https://aasldpubs.onlinelibrary.wiley.com/doi/pdf/10.1002/hep.1840050305

Plasma clearance of intravenously injected aspartate aminotransferase isozymes: evidence for preferential uptake by sinusoidal liver cells.

https://aasldpubs.onlinelibrary.wiley.com/doi/pdf/10.1002/hep.1840050306

Hepatic clearance of rat liver aspartate aminotransferase isozymes: Evidence for endocytotic uptake via different binding sites on sinusoidal liver cells

M D Seikoh Horiuchi

Papers

Plasma clearance of intravenously injected aspartate aminotransferase isozymes: evidence for preferential uptake by sinusoidal liver cells.

Hepatic clearance of rat liver aspartate aminotransferase isozymes: Evidence for endocytotic uptake via different binding sites on sinusoidal liver cells