M
M. Huber
Researcher at University of Zurich
Publications - 6
Citations - 1097
M. Huber is an academic researcher from University of Zurich. The author has contributed to research in topics: Measles virus & RNA. The author has an hindex of 5, co-authored 6 publications receiving 1064 citations.
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Journal ArticleDOI
Rescue of measles viruses from cloned DNA.
Frank Radecke,Pius Spielhofer,Henriette Schneider,Karin Kaelin,M. Huber,C. Dötsch,G. Christiansen,Martin A. Billeter +7 more
TL;DR: This system, in principle, should be applicable to the rescue of any member of the large virus order Mononegavirales, i.e. viruses with a nonsegmented negative‐strand RNA genome.
Journal ArticleDOI
Measles virus phosphoprotein retains the nucleocapsid protein in the cytoplasm.
M. Huber,Roberto Cattaneo,Pius Spielhofer,Claes Örvell,Erling Norrby,Erling Norrby,Marius Messerli,Jean Claude Perriard,Martin A. Billeter +8 more
TL;DR: Measles virus proteins were efficiently expressed in COS and Vero cells from vectors based on the strong cytomegalovirus enhancer-promoter and the simian virus 40 origin of replication to analyze in vivo the interactions between the N and P proteins.
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Domains of the Measles Virus N Protein Required for Binding to P Protein and Self-Assembly
TL;DR: The nucleocapsid protein (N, 525 amino acids) of measles virus plays a central role in the replication of the viral genomic RNA, and the domains on the N protein that promote binding to P protein and self-assembly have been identified utilizing a series of N protein deletions.
Journal ArticleDOI
Generation and properties of measles virus mutations typically associated with subacute sclerosing panencephalitis.
Martin A. Billeter,Roberto Cattaneo,Pius Spielhofer,Karin Kaelin,M. Huber,Anita M. Schmid,K. Baczko,Volker ter Meulen +7 more
TL;DR: It is concluded that mutations in the MV genes arise not only individually, by errors of the MV polymerase, but also in clusters as hypermutations, presumably due to RNA unwinding/modifying activity altering accidentally formed double-stranded RNA regions.
Journal ArticleDOI
Functional and nonfunctional measles virus matrix genes from lethal human brain infections.
TL;DR: In this article, the M gene of an infectious full-length genomic cDNA (from vaccine strain Edmonston) was replaced with different M genes derived from four patients with SSPE.