K
Karin Kaelin
Researcher at University of Zurich
Publications - 10
Citations - 1875
Karin Kaelin is an academic researcher from University of Zurich. The author has contributed to research in topics: Measles virus & Virus. The author has an hindex of 9, co-authored 10 publications receiving 1830 citations. Previous affiliations of Karin Kaelin include Centre national de la recherche scientifique.
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Journal ArticleDOI
Rescue of measles viruses from cloned DNA.
Frank Radecke,Pius Spielhofer,Henriette Schneider,Karin Kaelin,M. Huber,C. Dötsch,G. Christiansen,Martin A. Billeter +7 more
TL;DR: This system, in principle, should be applicable to the rescue of any member of the large virus order Mononegavirales, i.e. viruses with a nonsegmented negative‐strand RNA genome.
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Measles virus editing provides an additional cysteine-rich protein
TL;DR: It is demonstrated here that the MV P gene also expresses a third product which is translated from mRNAs in which one G residue has been inserted after three genomically encoded Gs, a modification found in about 50% of the P m RNAs.
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Mutated and hypermutated genes of persistent measles viruses which caused lethal human brain diseases
Roberto Cattaneo,Anita M. Schmid,Pius Spielhofer,Karin Kaelin,K. Baczko,Volker ter Meulen,Jancu Pardowitz,Stephen Flanagan,Bert K. Rima,Stephen A. Udem,Martin A. Billeter +10 more
TL;DR: The present study of four persistent MVs revealed a high number of differences from a consensus sequence also in other genes, and classified four lytic and seven persistent MV strains on the basis of their sequences.
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Rescue of Synthetic Measles Virus Minireplicons: Measles Genomic Termini Direct Efficient Expression and Propagation of a Reporter Gene
Mohinderjit S. Sidhu,Mohinderjit S. Sidhu,John Chan,Karin Kaelin,Pius Spielhofer,Frank Radecke,Henriette Schneider,Malthi Masurekar,Peter C. Dowling,Peter C. Dowling,Martin A. Billeter,Stephen A. Udem +11 more
TL;DR: Sequence analyses confirmed that both the expected chimeric antigenome and mRNA products were transcribed and replicated with fidelity during serial passage, indicating that the chimeric RNA not only was encapsidated, transcribed, and replicated, but also packaged into virions.
Journal ArticleDOI
Chimeric Measles Viruses with a Foreign Envelope
Pius Spielhofer,Thomas Bächi,Thomas Fehr,Gudrun Christiansen,Roberto Cattaneo,Karin Kaelin,Martin A. Billeter,Hussein Y. Naim +7 more
TL;DR: It is suggested that it is feasible to construct MV variants bearing a variety of different envelopes for use as vaccines or for gene therapeutic purposes.