M
M. J. Warrell
Researcher at John Radcliffe Hospital
Publications - 30
Citations - 2524
M. J. Warrell is an academic researcher from John Radcliffe Hospital. The author has contributed to research in topics: Rabies & Rabies vaccine. The author has an hindex of 18, co-authored 30 publications receiving 2469 citations.
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Journal Article
Human cerebral malaria. A quantitative ultrastructural analysis of parasitized erythrocyte sequestration.
TL;DR: It is concluded that there is no evidence for an inflammatory or immune pathogenesis for human cerebral malaria and that the clinical effects probably relate to anoxia and the metabolic activities of the parasites.
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Severe Hypoglycemia and Hyperinsulinemia in Falciparum Malaria
Nicholas J. White,David A. Warrell,Pornthep Chanthavanich,Sornchai Looareesuwan,M. J. Warrell,Sanjeev Krishna,Dermot H. Williamson,Robert C. Turner +7 more
TL;DR: Observations indicate that in falciparum malaria quinine-induced insulin secretion may precipitate hypoglycemia, but other factors, including the large glucose requirements of the malaria parasites may also contribute.
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Rabies and other lyssavirus diseases
M. J. Warrell,David A. Warrell +1 more
TL;DR: The methods by which these neurotropic viruses hijack neurophysiological mechanisms while evading immune surveillance is beginning to be unravelled by studies of molecular motor transport systems.
Journal ArticleDOI
Management of Rabies in Humans
Alan Jackson,M. J. Warrell,Charles E. Rupprecht,Hildegund C. J. Ertl,Bernhard Dietzschold,Michael O'Reilly,Richard P. Leach,Zhen F. Fu,William H. Wunner,Thomas P. Bleck,Henry Wilde +10 more
TL;DR: No single therapeutic agent is likely to be effective, but a combination of specific therapies could be considered, including rabies vaccine, rabies immunoglobulin, monoclonal antibodies, ribavirin, interferon-alpha, and ketamine.
Journal ArticleDOI
Economical multiple-site intradermal immunisation with human diploid-cell-strain vaccine is effective for post-exposure rabies prophylaxis
M. J. Warrell,David A. Warrell,K.G. Nicholson,Pravan Suntharasamai,Pornthep Chanthavanich,Chaisin Viravan,Abha Sinhaseni,M.K. Chiewbambroongkiat,X. Pouradier-Duteil,Rod Phanfung,C. Xueref,Dusit Udomsakdi +11 more
TL;DR: An economical post-exposure regimen of Mérieux human diploid-cell-strain vaccine (HDCSV) was compared with Semple vaccine (SV), the most widely used vaccine in Asia and was at least as effective as SV.