P
Pornthep Chanthavanich
Researcher at Mahidol University
Publications - 95
Citations - 5031
Pornthep Chanthavanich is an academic researcher from Mahidol University. The author has contributed to research in topics: Dengue fever & Vaccination. The author has an hindex of 35, co-authored 93 publications receiving 4772 citations. Previous affiliations of Pornthep Chanthavanich include University of Oxford & Liverpool School of Tropical Medicine.
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Journal ArticleDOI
Protective efficacy of the recombinant, live-attenuated, CYD tetravalent dengue vaccine in Thai schoolchildren: a randomised, controlled phase 2b trial
Arunee Sabchareon,Derek Wallace,Chukiat Sirivichayakul,Kriengsak Limkittikul,Pornthep Chanthavanich,Saravudh Suvannadabba,Vithaya Jiwariyavej,Wut Dulyachai,Krisana Pengsaa,T. Anh Wartel,Annick Moureau,Melanie Saville,Alain Bouckenooghe,Simonetta Viviani,Nadia Tornieporth,Jean Lang +15 more
TL;DR: These data show for the first time that a safe vaccine against dengue is possible, and Dengue vaccine was well tolerated, with no safety signals after 2 years of follow-up after the first dose.
Journal ArticleDOI
Severe Hypoglycemia and Hyperinsulinemia in Falciparum Malaria
Nicholas J. White,David A. Warrell,Pornthep Chanthavanich,Sornchai Looareesuwan,M. J. Warrell,Sanjeev Krishna,Dermot H. Williamson,Robert C. Turner +7 more
TL;DR: Observations indicate that in falciparum malaria quinine-induced insulin secretion may precipitate hypoglycemia, but other factors, including the large glucose requirements of the malaria parasites may also contribute.
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Prediction, prevention, and mechanism of early (anaphylactic) antivenom reactions in victims of snake bites.
Prida Malasit,David A. Warrell,Pornthep Chanthavanich,Chaisin Viravan,Juthathip Mongkolsapaya,B Singhthong,C Supich +6 more
TL;DR: Higher doses of antivenom might induce the complement activation and formation of immune complexes (aggregates) that have been observed during the clinically more severe reactions associated with homologous immunoglobulin treatment.
Journal ArticleDOI
Safety and immunogenicity of tetravalent live-attenuated dengue vaccines in Thai adult volunteers: role of serotype concentration, ratio, and multiple doses.
Arunee Sabchareon,Jean Lang,Pornthep Chanthavanich,Sutee Yoksan,Remi Forrat,Phanorsi Attanath,Chukiate Sirivichayakul,Krisana Pengsaa,Chanathep Pojjaroen-Anant,Watcharee Chokejindachai,Achara Jagsudee,Jean Francois Saluzzo,Natth Bhamarapravati +12 more
TL;DR: Most volunteers experienced clinically moderate fever, headache, myalgia, eye pain or rash 7-11 days after injection, generally lasting three days or less, and Modest decreases in platelets and neutrophils were observed.
Journal ArticleDOI
Antigen-specific immunosuppression in human malaria due to Plasmodium falciparum.
May Ho,Webster Hk,Sornchai Looareesuwan,Wichai Supanaranond,Rodney E. Phillips,Pornthep Chanthavanich,David A. Warrell +6 more
TL;DR: The results indicate that blood-stage plasmodial infections may suppress responses important for immunity to malaria and so allow the parasite to survive and suggest that patients acutely or even recently infected with P. falciparum may not respond as well to a malaria vaccine as would uninfected individuals.