M
M. L. Westedt
Publications - 15
Citations - 2379
M. L. Westedt is an academic researcher. The author has contributed to research in topics: Rheumatoid arthritis & Arthritis. The author has an hindex of 9, co-authored 15 publications receiving 2285 citations.
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Journal ArticleDOI
Clinical and radiographic outcomes of four different treatment strategies in patients with early rheumatoid arthritis (the BeSt study): a randomized, controlled trial.
Yvonne P M Goekoop-Ruiterman,J.K. de Vries-Bouwstra,Cornelia F Allaart,D. Van Zeben,Pit J S M Kerstens,Johanna M. W. Hazes,A. H. Zwinderman,H. K. Ronday,K.H. Han,M. L. Westedt,Andreas H. Gerards,J.H.L.M. van Groenendael,Willem F. Lems,M V van Krugten,Ferdinand C. Breedveld,Ben A. C. Dijkmans +15 more
TL;DR: In patients with early RA, initial combination therapy including either prednisone or infliximab resulted in earlier functional improvement and less radiographic damage after 1 year than did sequential monotherapy or step-up combination therapy.
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Efficacy of methotrexate treatment in patients with probable rheumatoid arthritis: A double‐blind, randomized, placebo‐controlled trial
Henrike van Dongen,Jill van Aken,LR Lard,K. Visser,H. Karel Ronday,H M J Hulsmans,I. Speyer,M. L. Westedt,André Peeters,Cornelia F Allaart,René E. M. Toes,Ferdinand C. Breedveld,Tom W J Huizinga +12 more
TL;DR: This study provides evidence for the efficacy of MTX treatment in postponing the diagnosis of RA, as defined by the ACR 1987 criteria, and retarding radiographic joint damage in UA patients.
Journal ArticleDOI
Factors associated with the development of vasculitis in rheumatoid arthritis: results of a case-control study.
Alexandre E. Voskuyl,A. H. Zwinderman,M. L. Westedt,Jan P. Vandenbroucke,F. C. Breedveld,J. M. W. Hazes +5 more
TL;DR: The development of RV is associated with male gender, extra-articular features, and a severe course of RA as indicated by the presence of joint destruction and need for intensive treatment with antirheumatic drugs.
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Survival, comorbidities and joint damage 11 years after the COBRA combination therapy trial in early rheumatoid arthritis
Lilian H D van Tuyl,Maarten Boers,Willem F. Lems,Robert B Landewé,Huub Han,S J van der Linden,Mart A F J van de Laar,Rene Westhovens,J Christiaan van Denderen,M. L. Westedt,André Peeters,P. Jacobs,Tom W J Huizinga,Hans van de Brink,Ben A. C. Dijkmans,Alexandre E. Voskuyl +15 more
TL;DR: After 11 years, initial COBRA combination therapy resulted in numerically lower mortality and similar prevalence of comorbidity compared with initial SSZ monotherapy, and lower progression of joint damage suggests long-term disease modification.
Journal ArticleDOI
Remission induction therapy with methotrexate and prednisone in patients with early rheumatoid and undifferentiated arthritis (the IMPROVED study)
Kirsten V. C. Wevers-de Boer,K. Visser,L. Heimans,H. Karel Ronday,Esmeralda T. H. Molenaar,J Hans L M Groenendael,André Peeters,M. L. Westedt,Gerard Collée,Peter B J de Sonnaville,B. Grillet,Tom W J Huizinga,Cornelia F Allaart +12 more
TL;DR: Initial treatment with MTX and a tapered high dose of prednisone results in similarly high remission percentages after 4 months in RA patients, regardless of fulfilling the 1987 or 2010 criteria, and in UA patients.