M
M. Mentasti
Researcher at Public Health England
Publications - 30
Citations - 750
M. Mentasti is an academic researcher from Public Health England. The author has contributed to research in topics: Legionella pneumophila & Legionella. The author has an hindex of 15, co-authored 28 publications receiving 625 citations. Previous affiliations of M. Mentasti include Boston Children's Hospital & University Hospital of Wales.
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Journal ArticleDOI
Burkholderia cenocepacia Infections in Cystic Fibrosis Patients: Drug Resistance and Therapeutic Approaches.
Viola Camilla Scoffone,Laurent R. Chiarelli,Gabriele Trespidi,M. Mentasti,Giovanna Riccardi,Silvia Buroni +5 more
TL;DR: The clinical distribution of B. cenocepacia described in the last 6 years and methods for identification and classification of epidemic strains are presented and point out the urgent need of new and alternative therapies to improve CF patients’ life expectancy.
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Multiple major disease-associated clones of Legionella pneumophila have emerged recently and independently.
Sophia David,Sophia David,Christophe Rusniok,Christophe Rusniok,M. Mentasti,Laura Gomez-Valero,Laura Gomez-Valero,Simon R. Harris,Pierre Lechat,John A. Lees,Christophe Ginevra,Philippe Glaser,Philippe Glaser,Laurence Ma,Christiane Bouchier,Anthony Underwood,Sophie Jarraud,Timothy G. Harrison,Julian Parkhill,Carmen Buchrieser,Carmen Buchrieser +20 more
TL;DR: It is hypothesized that these STs have adapted to new man-made environmental niches, which may be linked by human infection and transmission, and are leading to a shared pool of allelic variants potentially contributing to their increased disease propensity.
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Application of Legionella pneumophila-specific quantitative real-time PCR combined with direct amplification and sequence-based typing in the diagnosis and epidemiological investigation of Legionnaires’ disease
TL;DR: The sensitivity of the qPCR was ∼30% greater than that of culture and direct typing on culture-negative PCR-positive samples resulted in full 7-allele profiles from 23/46, 5 to 6 alleles from 8/46 and ≥1 allele from 43/46 strains.
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Increased incidence of Mycoplasma pneumoniae infection in England and Wales in 2010: multiocus variable number tandem repeat analysis typing and macrolide susceptibility.
TL;DR: Multiocus variable number tandem repeat analysis typing and analysis of macrolide resistance markers indicate that at least nine known and two novel strain types were circulating in England and Wales during October 2010 to January 2011.
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Comparison of the Legionella pneumophila population structure as determined by sequence-based typing and whole genome sequencing
TL;DR: It is concluded thatSBT is usually a good proxy for the genetic lineage described by the whole genome, and therefore utility of SBT is still suitable until the technology and economics of high throughput sequencing reach the point where routine WGS of L. pneumophila isolates for outbreak investigation is feasible.