M
M. Michael Aruldhas
Researcher at University of Madras
Publications - 61
Citations - 2097
M. Michael Aruldhas is an academic researcher from University of Madras. The author has contributed to research in topics: Glutathione peroxidase & Glutathione reductase. The author has an hindex of 27, co-authored 61 publications receiving 1964 citations.
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Journal ArticleDOI
Chronic chromium exposure-induced changes in testicular histoarchitecture are associated with oxidative stress: study in a non-human primate (Macaca radiata Geoffroy)
M. Michael Aruldhas,S. Subramanian,P. Sekar,G. Vengatesh,Gowri Chandrahasan,P. Govindarajulu,Mohammad Abdulkader Akbarsha +6 more
TL;DR: CrVI disrupts spermatogenesis by inducing free radical toxicity, and supplementation of antioxidant vitamins may be beneficial to the affected subjects.
Journal ArticleDOI
Quercetin-induced growth inhibition and cell death in prostatic carcinoma cells (PC-3) are associated with increase in p21 and hypophosphorylated retinoblastoma proteins expression.
M.R. Vijayababu,P. Kanagaraj,A. Arunkumar,R. Ilangovan,M. Michael Aruldhas,Jagadeesan Arunakaran +5 more
TL;DR: It was concluded that quercetin inhibits prostate cancer cell proliferation by altering the expression of cell cycle regulators and apoptotic proteins.
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Effects of glucose and its modulation by insulin and estradiol on BMSC differentiation into osteoblastic lineages
V. Gopalakrishnan,R.C. Vignesh,Jagadeesan Arunakaran,M. Michael Aruldhas,Narasimhan Srinivasan +4 more
TL;DR: It is suggested that insulin and estradiol are able to contain the deleterious effect of high concentrations of glucose on BMSC-derived osteoblast proliferation and function.
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Effects of Vitamin C and E on PCB (Aroclor 1254) induced oxidative stress, androgen binding protein and lactate in rat Sertoli cells
J. Senthil kumar,Sivanantham Banudevi,M. Sharmila,Palaniappan Murugesan,Narasimhan Srinivasan,Karundevi Balasubramanian,M. Michael Aruldhas,Jagadeesan Arunakaran +7 more
TL;DR: The present study suggests that Aroclor 1254 exposure induces oxidative stress in rat Sertoli cells and furthermore that simultaneous administration of Vitamin C or E ameliorated these effects.
Journal ArticleDOI
Ameliorative effect of vitamins (α-tocopherol and ascorbic acid) on PCB (Aroclor 1254) induced oxidative stress in rat epididymal sperm
Gunasekaran Krishnamoorthy,P. Venkataraman,A. Arunkumar,R.C. Vignesh,M. Michael Aruldhas,Jagadeesan Arunakaran +5 more
TL;DR: The result of this experiment shows that PCB significantly decreases the level of alpha-tocopherol, ascorbic acid and GSH and the activities of SOD, CAT, GPx, GR and GST with elevated levels of ROS and LPO.