Journal ArticleDOI
Effects of Vitamin C and E on PCB (Aroclor 1254) induced oxidative stress, androgen binding protein and lactate in rat Sertoli cells
J. Senthil kumar,Sivanantham Banudevi,M. Sharmila,Palaniappan Murugesan,Narasimhan Srinivasan,Karundevi Balasubramanian,M. Michael Aruldhas,Jagadeesan Arunakaran +7 more
TLDR
The present study suggests that Aroclor 1254 exposure induces oxidative stress in rat Sertoli cells and furthermore that simultaneous administration of Vitamin C or E ameliorated these effects.About:
This article is published in Reproductive Toxicology.The article was published on 2004-12-01. It has received 101 citations till now. The article focuses on the topics: Vitamin E & Glutathione reductase.read more
Citations
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Journal ArticleDOI
Antioxidant systems and oxidative stress in the testes.
R. John Aitken,Shaun D. Roman +1 more
TL;DR: The testes contain an elaborate array of antioxidant enzymes and free radical scavengers to ensure that the twin spermatogenic and steroidogenic functions of this organ are not impacted by oxidative stress.
Journal ArticleDOI
New developments and novel therapeutic perspectives for vitamin C
Yi Li,Herb E. Schellhorn +1 more
TL;DR: This review examines recent studies on the regulation of transport mechanisms for vitamin C, related clinical ramifications, and potential implications in high-dose vitamin C therapy, and evaluates recent clinical and scientific evidence on the effects of this vitamin on cancer and CVD.
Journal ArticleDOI
Malathion-induced testicular toxicity in male rats and the protective effect of vitamins C and E.
TL;DR: Light microscopic investigations revealed that 4 weeks of malathion exposure was associated with necrosis and edema in the seminiferous tubules and interstitial tissues, and it appears that vitamins C and E are not completely protective.
Journal ArticleDOI
Acute, subacute and subchronic administration of methyl parathion-induced testicular damage in male rats and protective role of vitamins C and E
Meltem Uzunhisarcikli,Yusuf Kalender,Kerem Dirican,Suna Kalender,Ayse Ogutcu,Fatma Buyukkomurcu +5 more
TL;DR: In this paper, the effects of methyl parathion on the testes of rats were investigated at the end of 24 h, 4th and 7th weeks compared with a control group.
Journal ArticleDOI
Studies on the protective role of vitamin C and E against polychlorinated biphenyl (Aroclor 1254)—induced oxidative damage in Leydig cells
TL;DR: It is suggested that vitamin C and E have ameliorative role against adverse effects of PCB on Leydig cell steroidogenesis and antioxidant system and Aroclor 1254 treatment significantly reduced the serum LH, TSH, PRL, T4, testosterone and estradiol.
References
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Journal Article
Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
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Glutathione S-transferases. The first enzymatic step in mercapturic acid formation.
TL;DR: The purification of homogeneous glutathione S-transferases B and C from rat liver is described, and only transferases A and C are immunologically related.
Journal ArticleDOI
Involvement of the Superoxide Anion Radical in the Autoxidation of Pyrogallol and a Convenient Assay for Superoxide Dismutase
TL;DR: The autoxidation of pyrogallol was investigated in the presence of EDTA in the pH range 7.9–10.6, indicating an almost total dependence on the participation of the superoxide anion radical, O2·−, in the reaction.
Book
The Physiology of Reproduction
Ernst Knobil,J. D. Neill +1 more
TL;DR: The gametes, fertilization and early embryogenesis the reproductive systems - the female, the male the pituitary and the hypothalmus, and the reproductive processes and their control.
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Selenium: Biochemical Role as a Component of Glutathione Peroxidase
TL;DR: When hemolyzates from erythrocytes of selenium-deficient rats were incubated in vitro in the presence of ascorbate or H2O2, added glutathione failed to protect the hemoglobin from oxidative damage.