M
M Rengaraju
Researcher at Children's Hospital of Philadelphia
Publications - 2
Citations - 1444
M Rengaraju is an academic researcher from Children's Hospital of Philadelphia. The author has contributed to research in topics: Interleukin 12 & Natural killer cell. The author has an hindex of 2, co-authored 2 publications receiving 1427 citations.
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Journal ArticleDOI
Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mononuclear cells.
A D'Andrea,M Rengaraju,Nicholas Valiante,Jihed Chehimi,M Kubin,M Aste,S H Chan,M Kobayashi,D Young,E Nickbarg +9 more
TL;DR: It is determined that most EBV-transformed human B lymphoblastoid cell lines constitutively produce low levels of the p70 heterodimer and an excess of the free p40 chain, whereas Burkitt lymphoma-derived, T, myeloid, and many solid tumor-derived cell lines produce neither.
Journal ArticleDOI
Natural killer (NK) cell stimulatory factor increases the cytotoxic activity of NK cells from both healthy donors and human immunodeficiency virus-infected patients.
Jihed Chehimi,Stuart E. Starr,I Frank,M Rengaraju,Stephanie J. Jackson,C Llanes,M Kobayashi,B Perussia,D Young,E Nickbarg +9 more
TL;DR: The multiple biological effects of NKSF, its activity at very low molar concentrations, and its ability to synergize with other physiological stimuli suggest that NKSF/IL-12 is a lymphokine likely to have physiological importance and considerable therapeutic potential.