M
Maciej Gawlak
Researcher at Medical University of Warsaw
Publications - 22
Citations - 579
Maciej Gawlak is an academic researcher from Medical University of Warsaw. The author has contributed to research in topics: Prefrontal cortex & Patch clamp. The author has an hindex of 9, co-authored 21 publications receiving 496 citations. Previous affiliations of Maciej Gawlak include Nencki Institute of Experimental Biology.
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Experience-dependent plasticity and modulation of growth regulatory molecules at central synapses.
Simona Foscarin,Danilo Ponchione,Ermira Pajaj,Ketty Leto,Maciej Gawlak,Grzegorz M. Wilczynski,Ferdinando Rossi,Daniela Carulli +7 more
TL;DR: The observations show that the maintenance and growth-inhibitory function of perineuronal nets are regulated by a dynamic interplay between pre- and postsynaptic neurons, and external stimuli act on this interaction to facilitate neuritic growth by locally dampening the activity of inhibitory cues.
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High resolution in situ zymography reveals matrix metalloproteinase activity at glutamatergic synapses.
Maciej Gawlak,T. Górkiewicz,T. Górkiewicz,Adam Gorlewicz,Filip A. Konopacki,Leszek Kaczmarek,Grzegorz M. Wilczynski,Grzegorz M. Wilczynski +7 more
TL;DR: A high-resolution fluorescent in situ zymography (ISZ) technique, performed in thin sections of the alcohol-fixed and polyester wax-embedded brain tissue of the rat, which is superior to the current ISZ protocols and could be used to investigate proteinase involvement in a range of physiological and pathological phenomena in the nervous system.
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Hypertension in rats is associated with an increased permeability of the colon to TMA, a gut bacteria metabolite
Kinga Jaworska,Tomasz Huc,Emilia Samborowska,Leszek Dobrowolski,Klaudia Bielinska,Maciej Gawlak,Marcin Ufnal +6 more
TL;DR: In this article, the authors evaluated if hypertension was associated with changes in the colon permeability to trimethylamine (TMA), a TMAO precursor, and found that hypertensive rats show an increased permeability of the colon to TMA.
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Reward learning requires activity of matrix metalloproteinase-9 in the central amygdala
Ewelina Knapska,Victoria Lioudyno,Anna Kiryk,Marta Mikosz,Tomasz Gorkiewicz,Tomasz Gorkiewicz,Piotr Michaluk,Maciej Gawlak,Mayank Chaturvedi,Gabriela Mochol,Marcin Balcerzyk,Daniel K. Wójcik,Grzegorz M. Wilczynski,Leszek Kaczmarek +13 more
TL;DR: It is reported that matrix metalloproteinase-9 (MMP-9, extracellularly operating enzyme) in the central nucleus of the amygdala (CeA) is crucial for appetitive, but not for aversive, learning in mice.
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The extracellular matrix glycoprotein tenascin-C and matrix metalloproteinases modify cerebellar structural plasticity by exposure to an enriched environment
Vera Stamenković,Stefan Stamenković,Tomasz Jaworski,Maciej Gawlak,Milos Jovanovic,Igor Jakovcevski,Grzegorz M. Wilczynski,Leszek Kaczmarek,Melitta Schachner,Melitta Schachner,Lidija Radenovic,Pavle R. Andjus +11 more
TL;DR: The present study suggests that TnC contributes to the regulation of structural plasticity in the cerebellum and that interactions between TNC and MMP-9 are likely to be important for these processes to occur.