Magnus Unemo

TL;DR: Estimates of the global prevalence and incidence of chlamydia, gonorrhoea, trichomoniasis, and syphilis in adult women and men remain high, with nearly one million new infections with curable STI each day.

TL;DR: The study highlights the need to expand data collection efforts at country level and provides an initial baseline for monitoring progress of the World Health Organization global health sector strategy on sexually transmitted infections 2016–2021.

TL;DR: By understanding the evolution, emergence, and spread of AMR in N. gonorrhoeae, including its molecular and phenotypic mechanisms, resistance to antimicrobials used clinically can be anticipated, and future methods for genetic testing for AMR might permit region-specific and tailor-made antimicrobial therapy, the design of novel antimicroBials to circumvent the resistance problems can be undertaken more rationally.

TL;DR: A detailed characterization of the first Neisseria gonorrhoeae strain, H041, was performed to confirm the finding, examine its antimicrobial resistance (AMR), and elucidate the resistance mechanisms.

TL;DR: F89 has high-level resistance to cefixime and ceftriaxone and resistance to most other antimicrobials examined and is assigned to MLST sequence type 1901 and NG-MAST ST1407, which is a successful gonococcal clone that has spread globally.