D
Daniel Golparian
Researcher at Örebro University
Publications - 123
Citations - 5716
Daniel Golparian is an academic researcher from Örebro University. The author has contributed to research in topics: Neisseria gonorrhoeae & Antibiotic resistance. The author has an hindex of 34, co-authored 105 publications receiving 4558 citations. Previous affiliations of Daniel Golparian include World Health Organization.
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Journal ArticleDOI
Is Neisseria gonorrhoeae Initiating a Future Era of Untreatable Gonorrhea?: Detailed Characterization of the First Strain with High-Level Resistance to Ceftriaxone
Makoto Ohnishi,Daniel Golparian,Ken Shimuta,Takeshi Saika,Shinji Hoshina,Kazuhiro Iwasaku,Shu Ichi Nakayama,Jo Kitawaki,Magnus Unemo +8 more
TL;DR: A detailed characterization of the first Neisseria gonorrhoeae strain, H041, was performed to confirm the finding, examine its antimicrobial resistance (AMR), and elucidate the resistance mechanisms.
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High-level cefixime- and ceftriaxone-resistant Neisseria gonorrhoeae in France: novel penA mosaic allele in a successful international clone causes treatment failure.
Magnus Unemo,Daniel Golparian,Robert A. Nicholas,Makoto Ohnishi,Anne Gallay,Patrice Sednaoui +5 more
TL;DR: F89 has high-level resistance to cefixime and ceftriaxone and resistance to most other antimicrobials examined and is assigned to MLST sequence type 1901 and NG-MAST ST1407, which is a successful gonococcal clone that has spread globally.
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Failure of Dual Antimicrobial Therapy in Treatment of Gonorrhea
Helen Fifer,Usha Natarajan,Lucy Jones,Sarah Alexander,Gwenda Hughes,Daniel Golparian,Magnus Unemo +6 more
TL;DR: The clinical failure of ceftriaxone and azithromycin in a patient with gonorrhea is described.
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Gonorrhoea treatment failure caused by a Neisseria gonorrhoeae strain with combined ceftriaxone and high-level azithromycin resistance, England, February 2018
David W Eyre,Nicholas D Sanderson,Emily Lord,Natasha Regisford-Reimmer,Kevin K Chau,Leanne Barker,Markus Morgan,Robert Newnham,Daniel Golparian,Magnus Unemo,Derrick W. Crook,Derrick W. Crook,Derrick W. Crook,Tim E. A. Peto,Tim E. A. Peto,Gwenda Hughes,Michelle J Cole,Helen Fifer,Anne Edwards,Monique Andersson +19 more
TL;DR: A heterosexual male was diagnosed with gonorrhoea in the United Kingdom following sexual intercourse with a locally resident female in Thailand and failed treatment with ceftriaxone plus doxycycline and subsequently spectinomycin, resulting in resistance arose from two mechanisms combining for the first time in a genetic background similar to a commonly circulating strain.
Journal ArticleDOI
The novel 2016 WHO Neisseria gonorrhoeae reference strains for global quality assurance of laboratory investigations: phenotypic, genetic and reference genome characterization.
Magnus Unemo,Daniel Golparian,Leonor Sánchez-Busó,Yonatan H. Grad,Yonatan H. Grad,Susanne Jacobsson,Makoto Ohnishi,Monica M Lahra,Athena Limnios,Aleksandra E. Sikora,Teodora Wi,Simon R. Harris +11 more
TL;DR: The phenotypic, genetic and reference genome characteristics of the 2016 WHO gonococcal reference strains intended for quality assurance in the WHO global GASP, other GASPs, diagnostics and research worldwide are described.