M
Mahantesh S. Navati
Researcher at Albert Einstein College of Medicine
Publications - 29
Citations - 933
Mahantesh S. Navati is an academic researcher from Albert Einstein College of Medicine. The author has contributed to research in topics: Nitric oxide & Nitrite. The author has an hindex of 11, co-authored 29 publications receiving 782 citations.
Papers
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Journal ArticleDOI
Curcumin-encapsulated nanoparticles as innovative antimicrobial and wound healing agent
Aimee Krausz,Brandon L. Adler,Vitor Cabral,Mahantesh S. Navati,Jessica Doerner,Rabab A. Charafeddine,Dinesh Chandra,Hongying Liang,Leslie Gunther,Alicea Clendaniel,Stacey L. Harper,Joel M. Friedman,Joshua D. Nosanchuk,Adam J. Friedman +13 more
TL;DR: In this article, the authors synthesized and characterized curcumin nanoparticles (curc-np), which inhibited in vitro growth of methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa in dose-dependent fashion.
Journal ArticleDOI
Sustained release nitric oxide releasing nanoparticles: Characterization of a novel delivery platform based on nitrite containing hydrogel/glass composites ☆
Adam J. Friedman,George Han,Mahantesh S. Navati,Manju Chacko,Leslie Gunther,Alan A. Alfieri,Joel M. Friedman +6 more
TL;DR: The presented data raise the prospect that these new NO releasing nanoparticles can be easily formulated for use under a wide range of therapeutic circumstances.
Journal ArticleDOI
Curcumin slows osteoarthritis progression and relieves osteoarthritis-associated pain symptoms in a post-traumatic osteoarthritis mouse model.
Zhuo Zhang,Zhuo Zhang,Daniel J. Leong,Lin Xu,Zhiyong He,Angela Wang,Mahantesh S. Navati,Sun J. Kim,David M. Hirsh,John A. Hardin,Neil J. Cobelli,Joel M. Friedman,Hui B. Sun +12 more
TL;DR: First evidence is provided that curcumin significantly slows OA disease progression and exerts a palliative effect in an OA mouse model, as indicated by reduced tactile hypersensitivity and improved locomotor behavior.
Journal ArticleDOI
Unfolding and refolding of Sol - Gel encapsulated carbonmonoxymyoglobin: An orchestrated spectroscopic study of intermediates and kinetics
Uri Samuni,Mahantesh S. Navati,Laura J. Juszczak,David Dantsker,Mary Qu Yang,Joel M. Friedman +5 more
TL;DR: The pH-induced unfolding and refolding of the carbon monoxide-bound derivative of horse skeletal myoglobin encapsulated in porous sol−gels is probed using several optical techniques in conjunction with different unfolding/refolding protocols.
Patent
Compositions for sustained release of nitric oxide, methods of preparing same and uses thereof
TL;DR: In this article, the authors provide compositions for releasing nitric oxide (NO) comprising a matrix that encapsulates nitric dioxide, which is released when the composition is exposed to an aqueous environment and further provides methods of preparing the compositions and uses of the compositions for treating infections and disorders.