M
Mahefatiana Andrianifahanana
Researcher at University of Nebraska Medical Center
Publications - 13
Citations - 1158
Mahefatiana Andrianifahanana is an academic researcher from University of Nebraska Medical Center. The author has contributed to research in topics: Pancreas & Pancreatic cancer. The author has an hindex of 11, co-authored 12 publications receiving 1104 citations. Previous affiliations of Mahefatiana Andrianifahanana include Eppley Institute for Research in Cancer and Allied Diseases.
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Journal ArticleDOI
Regulation of mucin expression: mechanistic aspects and implications for cancer and inflammatory diseases.
TL;DR: Some physiologically relevant regulatory aspects of mucin production are discussed, with a particular emphasis on aberrations that pertain to pathological situations.
Journal Article
Mucin (MUC) Gene Expression in Human Pancreatic Adenocarcinoma and Chronic Pancreatitis: A Potential Role of MUC4 as a Tumor Marker of Diagnostic Significance
Mahefatiana Andrianifahanana,Nicolas Moniaux,Bruno M. Schmied,Jörg Ringel,Helmut Friess,Michael A. Hollingsworth,Markus W. Büchler,Jean-Pierre Aubert,Surinder K. Batra +8 more
TL;DR: It is demonstrated that pancreatic mucin MUC4 is a tumor-associated mucin, and a novel avenue to discriminate between pancreatic adenocarcinoma and pancreatitis is introduced.
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Multiple roles of mucins in pancreatic cancer, a lethal and challenging malignancy.
Nicolas Moniaux,Mahefatiana Andrianifahanana,Randall E. Brand,Surinder K. Batra,Surinder K. Batra +4 more
TL;DR: The factors that contribute to the lethality of pancreatic cancer as well as the key role played by mucins, particularly MUC1 and MUC4, in the development and progression of the disease are discussed.
Journal ArticleDOI
Chronic pancreatic inflammation induced by environmental tobacco smoke inhalation in rats.
Uwe A. Wittel,Krishan K. Pandey,Mahefatiana Andrianifahanana,Sonny L. Johansson,Diane M. Cullen,Mohammed P. Akhter,Randall E. Brand,Bogdain Prokopczyk,Surinder K. Batra +8 more
TL;DR: Experimental evidence of morphological pancreatic damage induced by the inhalation of cigarette smoke is provided, which is likely to be mediated by alterations of acinar cell function.
Journal ArticleDOI
Generation and Characterization of Anti-MUC4 Monoclonal Antibodies Reactive with Normal and Cancer Cells in Humans
Nicolas Moniaux,Grish C. Varshney,Subhash C. Chauhan,Marie Christine Copin,Maneesh Jain,Uwe A. Wittel,Mahefatiana Andrianifahanana,Jean-Pierre Aubert,Surinder K. Batra +8 more
TL;DR: Anti-MUC4 MAb may represent a powerful tool for the study of MUC4 function under normal and pathological conditions and for diagnosis of solid tumors including those in the breast, pancreas, lungs, and ovaries.