M
Mahesh S. Karandikar
Publications - 5
Citations - 153
Mahesh S. Karandikar is an academic researcher. The author has contributed to research in topics: Adiponectin & Pancreatectomy. The author has an hindex of 3, co-authored 5 publications receiving 131 citations.
Papers
More filters
Journal ArticleDOI
Multigenerational Undernutrition Increases Susceptibility to Obesity and Diabetes that Is Not Reversed after Dietary Recuperation.
Anandwardhan A. Hardikar,Sarang N. Satoor,Mahesh S. Karandikar,Mugdha V. Joglekar,Amrutesh S. Puranik,Wilson K. M. Wong,Sandeep Kumar,Amita Limaye,Dattatray S. Bhat,Andrzej S. Januszewski,Malati R. Umrani,Amaresh K. Ranjan,Kishori G Apte,Pranav Yajnik,Ramesh R. Bhonde,Sanjeev Galande,Anthony C Keech,Alicia J. Jenkins,Chittaranjan S. Yajnik +18 more
TL;DR: Altered epigenetic signatures in insulin-2 gene promoter region of Undernourished rats are not reversed by nutrient recuperation, and may contribute to the persistent detrimental metabolic profiles in similar multigenerational undernourishing human populations.
Journal ArticleDOI
Effect of partial pancreatectomy on diabetic status in BALB/c mice
TL;DR: It has been shown that induction of a regenerative stimulus (pancreatectomy) in conditions of STZ-induced diabetes may trigger pancreatic regenerative processes, thereby restoring a functional pancreas, in STz-diabetic mice.
Journal ArticleDOI
Location, location, location: Beneficial effects of autologous fat transplantation.
Sarang N. Satoor,Amrutesh S. Puranik,Sandeep Kumar,Michael D. Williams,Mallikarjun Ghale,Anand Rahalkar,Mahesh S. Karandikar,Yogesh S. Shouche,Milind S. Patole,Ramesh R. Bhonde,Chittaranjan S. Yajnik,Anandwardhan A. Hardikar +11 more
TL;DR: It is shown here that active transcriptional state of adipokine genes is linked with glucose mediated recruitment of enzymes that regulate histone methylation, and autologous transplantation of visceral fat to subcutaneous sites offers metabolic advantage.
Book ChapterDOI
Promoting Pro-Endocrine Differentiation and Graft Maturation Following Surgical Resection of the Mouse Pancreas.
Mugdha V. Joglekar,Rohan R. Patil,Sarang N. Satoor,Wilson K. M. Wong,Mahesh S. Karandikar,Anandwardhan A. Hardikar +5 more
TL;DR: In this article, the authors employed a novel strategy to improve the efficiency of progenitor cell differentiation by performing partial mouse pancreas resection after transplanting in vitro generated insulin-producing cells under the kidney capsule of these mice.
Posted ContentDOI
Circulating microRNAs from early childhood and adolescence are associated with pre-diabetes at 18 years of age in women from the PMNS cohort
Mugdha V. Joglekar,Pooja Kunte,Wilson K. M. Wong,Dattatray S. Bhat,Sarang N. Satoor,Rohan R. Patil,Mahesh S. Karandikar,Caroline H.D. Fall,Chittaranjan S. Yajnik,Anandwardhan A. Hardikar +9 more
TL;DR: In this paper, the authors provided preliminary longitudinal analyses of circulating microRNAs in normal glucose tolerant (NGT@18y, N=10) and glucose intolerant (N=8) women (ADA criteria) at 6-, 12- and 17-years of their age using discovery analysis (OpenArray platform).