M
Maire Doyle
Researcher at University of Florida
Publications - 11
Citations - 769
Maire Doyle is an academic researcher from University of Florida. The author has contributed to research in topics: CTL* & Cytotoxic T cell. The author has an hindex of 6, co-authored 11 publications receiving 707 citations.
Papers
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Journal ArticleDOI
Mechanisms of action of glucagon-like peptide 1 in the pancreas
Maire Doyle,Josephine M. Egan +1 more
TL;DR: Although these latter effects cannot be currently monitored in humans, there are substantial improvements in glucose tolerance and increases in both first phase and plateau phase insulin secretory responses in T2DM patients treated with Ex-4.
Resveratrol Prevents βcell Dedifferentiation in NonHuman Primates Given a High Fat/ High Sugar Diet Running Title: Resveratrol Reverses the Effect of HFS Diets
Jennifer L. Fiori,Yu-Kyong Shin,Wook Kim,Susan M. Krzysik-Walker,Olga D. Carlson,Mitesh Sanghvi,Ruin Moaddel,Kathleen Farhang,Maire Doyle,Kevin J. Pearson,Julie A. Mattison,Rafael de Cabo,Josephine Egan +12 more
TL;DR: This paper showed that resveratrol supplementation reduces blood glucose, preserves β-cells in islets of Langerhans, and improves insulin action in non-human primates, such as Rhesus monkeys.
Journal ArticleDOI
Autoimmune dacryoadenitis of NOD/LtJ mice and its subsequent effects on tear protein composition.
Maire Doyle,Lori L. Boggs,Robert Attia,Lauren R. Cooper,Daniel R. Saban,Cuong Q. Nguyen,Ammon B. Peck +6 more
TL;DR: Using this model, potentially important pathophysiological mechanisms of the autoimmune attack and possible diagnostic markers for development of SjS-associated dacryoadenitis can be identified.
Journal ArticleDOI
Sjögren's syndrome-like disease of C57BL/6.NOD-Aec1 Aec2 mice: gender differences in keratoconjunctivitis sicca defined by a cross-over in the chromosome 3 Aec1 locus.
Cuong Q. Nguyen,Eric Singson,J.-Y. Kim,Janet G. Cornelius,R. Attia,Maire Doyle,Marievic Bulosan,Seunghee Cha,Ammon B. Peck +8 more
TL;DR: It is suggested that SjS‐like disease in the NOD mouse shows gender‐specific regulation determined by autosomal genes, whereas female mice exhibit stomatitis sicca in the absence of detectable keratoconjunctivitis sICca.
Patent
Uses of Notch Receptors, Notch Ligands, and Notch Modulators in Methods Related to Metabolic Diseases
Josephine Egan,Maire Doyle +1 more
TL;DR: In this article, the authors proposed methods for identifying and isolating a precursor cell, increasing insulin synthesis from a pancreatic β-cell, and improving pancreatic α-cell function.