Maitreyee Bhattacharyya

TL;DR: Genetic mutations for factor V Leiden, prothrombin gene 20210A, and methyltetrahydrofolate reductase (MTHFR) C677T were studied in Budd-Chiari syndrome and portal vein thrombosis patients for underlying inherited prothROMbotic defects such as protein C, protein S, and antithrombin III deficiencies.

TL;DR: Genetic mutations for factor V Leiden, prothrombin gene 20210A, and methyltetrahydrofolate reductase (MTHFR) C677T were studied in Budd-Chiari syndrome and portal vein thrombosis patients for underlying inherited prothROMbotic defects such as protein C, protein S, and antithrombin III deficiencies.

TL;DR: It is suggested that expression of a procoagulant surface by thalassemia intermedia red blood cells may be the major underlying factor giving rise to platelet and coagulation inhibitor abnormalities in these patients, not related to iron overload or hepatic dysfunction.

TL;DR: To investigate the cause and effects of intracellular iron overload in lymphocytes of thalassemia major patients, a large number of patients with this condition have suffered from iron overload.

TL;DR: 431 patients with thrombosis of different venous system were evaluated for underlying acquired and inherited prothrombotic states and deficiency of protein C, protein S and AT III were attributed to inherited factors as no associated acquired risk factor was present.