M
Maki Tanaka
Researcher at Sapporo Medical University
Publications - 28
Citations - 581
Maki Tanaka is an academic researcher from Sapporo Medical University. The author has contributed to research in topics: Cell culture & Cancer. The author has an hindex of 12, co-authored 28 publications receiving 517 citations. Previous affiliations of Maki Tanaka include Health Sciences University of Hokkaido.
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Journal ArticleDOI
Ex Vivo Large-Scale Generation of Human Platelets from Cord Blood CD34+ Cells
Takuya Matsunaga,Ikuta Tanaka,Masayoshi Kobune,Yutaka Kawano,Maki Tanaka,Kageaki Kuribayashi,Satoshi Iyama,Tsutomu Sato,Yasushi Sato,Rishu Takimoto,Tetsuji Takayama,Junji Kato,Takafumi Ninomiya,Hirofumi Hamada,Yoshiro Niitsu +14 more
TL;DR: The CB‐derived PLTs exhibited features quite similar to those from peripheral blood in morphology, as revealed by electron micrographs, and in function, as shown by fibrinogen/ADP aggregation, with the appearance of P‐selectin and activated glycoprotein IIb‐IIIa antigens.
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Establishment of high- and low-invasion clones derived for a human tongue squamous-cell carcinoma cell line SAS.
TL;DR: Five clones with different invasiveness, defined by endothelial cell monolayer assay, are established from the human oral SCC cell line SAS by a limiting-dilution method, finding that SAS-H1 exhibited a higher migration ability than SAS-L1 and this pair of clones would be a useful experimental model to help in the study of the invasion and metastasis of human Oral SCC.
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Treatment of murine collagen-induced arthritis by ex vivo extracellular superoxide dismutase gene transfer.
Satoshi Iyama,Tetsuro Okamoto,Tsutomu Sato,Naofumi Yamauchi,Yasushi Sato,Katsunori Sasaki,Minoru Takahashi,Maki Tanaka,Tetsuo Adachi,Katsuhisa Kogawa,Junji Kato,Sumio Sakamaki,Yoshiro Niitsu +12 more
TL;DR: In this paper, the authors examined the efficacy of extracellular superoxide dismutase (EC-SOD) gene therapy in murine collagen-induced arthritis and found that mice treated with the transgene exhibited significant suppression of clinical symptoms such as disabling joint swelling, deformity, and hind paw thickness.
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Iron/IRP-1-dependent regulation of mRNA expression for transferrin receptor, DMT1 and ferritin during human erythroid differentiation
Junji Kato,Masayoshi Kobune,Shunichi Ohkubo,Koshi Fujikawa,Maki Tanaka,Rishu Takimoto,Kohichi Takada,Daisuke Takahari,Yutaka Kawano,Yutaka Kohgo,Yoshiro Niitsu +10 more
TL;DR: The results suggest that IRP-1/IRE interactions, which are supposedly induced after sensing a decrease of the intracellular non-Heme iron levels, play a crucial role on the posttranscriptional regulation of TfR, DMT1, and ferritin mRNAs during differentiation of normal human erythropoietic cells.
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Prevalence of human anti-mouse antibodies (HAMAs) in routine examinations
Saori Koshida,Koichi Asanuma,Kageaki Kuribayashi,Maki Goto,Naoki Tsuji,Daisuke Kobayashi,Maki Tanaka,Naoki Watanabe +7 more
TL;DR: An enzyme-linked immunosorbent assay (ELISA) was developed to detect human anti-mouse antibodies (HAMAs) in routine examinations and a considerable number of HAMA-positive samples, reacting with the heavy chain of mIg, were found.