M
Makiko Yamashita
Researcher at Kyushu University
Publications - 44
Citations - 443
Makiko Yamashita is an academic researcher from Kyushu University. The author has contributed to research in topics: Antibody & Antigen. The author has an hindex of 10, co-authored 44 publications receiving 415 citations.
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Journal ArticleDOI
Detection of Magnetic Nanoparticles with Superconducting Quantum Interference Device (SQUID) Magnetometer and Application to Immunoassays
Keiji Enpuku,Tadashi Minotani,Takemitsu Gima,Yukinori Kuroki,Yuzuru Itoh,Makiko Yamashita,Yoshinori Katakura,Satoru Kuhara +7 more
TL;DR: In this paper, a superconducting quantum interference device (SQUID) magnetometer was used to measure biological antigen-antibody reactions with magnetic nanoparticles of γ-Fe2O3.
Journal ArticleDOI
Recent advances in the generation of human monoclonal antibody.
TL;DR: A method to generate human mAbs is independently developed by combining the method of in vitro immunization using peripheral blood mononuclear cells and the phage display method.
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IL-10 Augments Antibody Production in in Vitro Immunized Lymphocytes by Inducing a Th2-Type Response and B Cell Maturation
Qianghua Xu,Qianghua Xu,Qianghua Xu,Yoshinori Katakura,Makiko Yamashita,Sheng-Guo Fang,Sheng-Guo Fang,Takashi Tamura,Shin Ei Matsumoto,Yoshihiro Aiba,Kiichiro Teruya,Kazuhiro Osada,Ryuhei Nishikawa,Sanetaka Shirahata +13 more
TL;DR: The results indicated that IL-10 plays an important role in setting the cellular milieu to produce antibodies in an IVI protocol by clarifying the cytokine expression profiles in CD4+ and CD8+ T cells.
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Protein Kinase C δ Plays a Key Role in Cellular Senescence Programs of Human Normal Diploid Cells
Yoshinori Katakura,Miyako Udono,Kazuyuki Katsuki,Hisaya Nishide,Yukiko Tabira,Takahiro Ikei,Makiko Yamashita,Tsukasa Fujiki,Sanetaka Shirahata +8 more
TL;DR: It is suggested that the induction of senescence and hTERT repression are coordinately regulated by PKC-delta, which was shown to function in human telomerase reverse transcriptase (hTERT) gene repression.
Journal ArticleDOI
Production of Human Monoclonal Antibodies against FcεRIα by a Method Combining in Vitro Immunization with Phage Display
Kosuke Tomimatsu,Shin Ei Matsumoto,Makiko Yamashita,Kiichiro Teruya,Yoshinori Katakura,Shigeru Kabayama,Sanetaka Shirahata +6 more
TL;DR: The results suggest that one can obtain membrane protein-specific human monoclonal antibodies from a relatively small phage antibody library using in vitro immunized PBMCs.