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Makoto Kinoshita

Researcher at University of Tokyo

Publications -  131
Citations -  4799

Makoto Kinoshita is an academic researcher from University of Tokyo. The author has contributed to research in topics: Experimental autoimmune encephalomyelitis & Vestibular system. The author has an hindex of 31, co-authored 129 publications receiving 4150 citations. Previous affiliations of Makoto Kinoshita include Teikyo University & Osaka University.

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Commensal bacteria-dependent indole production enhances epithelial barrier function in the colon

TL;DR: Oral administration of indole-containing capsules resulted in increased expression of both tight junction (TJ)- and adherens junction (AJ)-associated molecules in colonic ECs in GF mice, which showed higher resistance to dextran sodium sulfate (DSS)-induced colitis and a similar protective effect of indoles on DSS-induced epithelial damage was also observed in mice bred in SPF conditions.