M
Malapaka Kiranmayi
Researcher at Indian Institute of Technology Madras
Publications - 3
Citations - 65
Malapaka Kiranmayi is an academic researcher from Indian Institute of Technology Madras. The author has contributed to research in topics: Receptor & Baroreflex. The author has an hindex of 2, co-authored 3 publications receiving 45 citations.
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Journal ArticleDOI
Catestatin: A Master Regulator of Cardiovascular Functions.
TL;DR: These multitude of effects establish CST as a master regulator of cardiovascular functions and support for a direct functional role of CST in the failing myocardium is provided.
Journal ArticleDOI
Catestatin Gly364Ser Variant Alters Systemic Blood Pressure and the Risk for Hypertension in Human Populations via Endothelial Nitric Oxide Pathway
Malapaka Kiranmayi,Venkat R. Chirasani,Prasanna K.R. Allu,Prasanna K.R. Allu,Lakshmi Subramanian,Elizabeth E Martelli,Bhavani S. Sahu,Bhavani S. Sahu,Durairajpandian Vishnuprabu,Rathnakumar Kumaragurubaran,Saurabh Sharma,Dhanasekaran Bodhini,Madhulika Dixit,Arasambattu Kannan Munirajan,Madhu Khullar,Venkatesan Radha,Viswanathan Mohan,Ajit S. Mullasari,Sathyamangla V. Naga Prasad,Sanjib Senapati,Nitish R. Mahapatra +20 more
TL;DR: CST-364Ser allele enhanced the risk for hypertension in human populations, possibly via diminished endothelial NO production because of altered interactions of CST-364 Ser peptide with ADRB2 as compared with CST-WT.
Journal ArticleDOI
A haplotype variant of the human chromogranin A gene (CHGA) promoter increases CHGA expression and the risk for cardiometabolic disorders
Lakshmi Subramanian,Abrar A. Khan,Prasanna K.R. Allu,Malapaka Kiranmayi,Bhavani S. Sahu,Saurabh Sharma,Madhu Khullar,Ajit S. Mullasari,Nitish R. Mahapatra +8 more
TL;DR: A functional role of the CHGA promoter haplotypes 2 (occurring in a large proportion of the world population) in enhancing CHGA expression in haplotype 2 carriers who may be at higher risk for cardiovascular/metabolic disorders is suggested.