M
Malgorzata Czyz
Researcher at Medical University of Łódź
Publications - 108
Citations - 2886
Malgorzata Czyz is an academic researcher from Medical University of Łódź. The author has contributed to research in topics: Melanoma & Apoptosis. The author has an hindex of 28, co-authored 101 publications receiving 2393 citations. Previous affiliations of Malgorzata Czyz include University of Kentucky & University of Auckland.
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MITF in melanoma: mechanisms behind its expression and activity
TL;DR: The complexity of a multilevel regulation of MITF expression and activity that underlies distinct context-related phenotypes of melanoma and might explain diverse responses of melanomas patients to currently used therapeutics is discussed.
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Increased protein glycation in diabetes mellitus is associated with decreased aspirin-mediated protein acetylation and reduced sensitivity of blood platelets to aspirin
Cezary Watala,Justyna Pluta,Jacek Golanski,Marcin Rozalski,Malgorzata Czyz,Zygmunt Trojanowski,Józef Drzewoski +6 more
TL;DR: In this article, the authors used whole-blood impedance aggregometry and platelet function analyzer (PFA-100) to monitor the chemical background of how chronic hyperglycemia affects platelet response to ASA in diabetes and study a chemical competition between the amount of bound acetyl residues and the extent of protein glycation in blood platelets.
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MiRNA in melanoma-derived exosomes
TL;DR: The current knowledge with regard to miRNAs that are found in exosomes derived from tumors, particularly from melanoma is summarized.
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WNT Signaling in Melanoma.
TL;DR: The current view on the role of the WNT-signaling in cancer immunity as well as a short summary of WNT pathway-related drugs under investigation are provided.
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Parthenolide, a sesquiterpene lactone from the medical herb feverfew, shows anticancer activity against human melanoma cells in vitro.
Karolina Lesiak,Kamila Koprowska,Izabela Zalesna,Dariusz Nejc,Markus Düchler,Malgorzata Czyz +5 more
TL;DR: Interestingly, the melanoma cells from vertical growth phase and melanocytes were less susceptible to parthenolide-induced cell death than metastatic cells when drug concentration was at least 6 μmol/l, suggesting the reaction with intracellular thiols as the mechanism responsible for parthenolate activity.