M
Manel Joaquin
Researcher at University of Cincinnati
Publications - 1
Citations - 787
Manel Joaquin is an academic researcher from University of Cincinnati. The author has contributed to research in topics: Kinase & Phosphatidylinositol. The author has an hindex of 1, co-authored 1 publications receiving 775 citations. Previous affiliations of Manel Joaquin include Novartis.
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Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase
Takahiro Nobukuni,Manel Joaquin,Manel Joaquin,Marta Roccio,Stephen G. Dann,So Young Kim,Pawan Gulati,Maya P. Byfield,Jonathan M. Backer,Francois Natt,Johannes L. Bos,Fried J. T. Zwartkruis,George Thomas,George Thomas +13 more
TL;DR: A major pathway by which amino acids control mTOR signaling is distinct from that of insulin and that, instead of signaling through components of the insulin/class 1PI3K pathway, amino acids mediate mTOR activation by signaling through class 3 PI3K, hVps34.