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Showing papers by "Manel Sabaté published in 1998"


Journal ArticleDOI
TL;DR: A new modality of dosimetry based on a method that three-dimensional (3-D) image reconstruction of electrocardiogram-gated intravascular ultrasound (IVUS) images is presented, supporting the use of DVH based on quantitative IVUS measurements for optimal dose prescription in vascular interventional radiation therapy.
Abstract: Application of ionizing radiation to prevent restenosis in atherosclerotic vessels treated by balloon angioplasty is a new treatment under investigation in interventional cardiology and radiology. There is variability in dose prescription, and both /spl gamma/- and /spl beta/-emitters are used, leading to a wide range of dose distribution over the arterial vessel wall. The authors present a new modality of dosimetry based on a method that three-dimensional (3-D) image reconstruction of electrocardiogram (ECG)-gated intravascular ultrasound (IVUS) images. Dose volume histograms (DVH) are used to describe the cumulative distribution of dose over two specific volumes: i) at the level of the luminal surface, defined with a thickness of 0.1 mm from the automatically detected contour of the highly echogenic blood-vessel interface, and ii) the adventitia volume is computed considering a 0.5-mm thickness from the echogenic media-adventitia interface. DVH provide a tool for reporting the actual delivered dose at the site believed to be the target: the adventitia, and to detect excessive radiation which could lead to vascular complications. Simulation of a /spl gamma/-emitter or of a radioactive source train in the center of the lumen are possible. The data obtained from the first ten patients included in the /spl beta/-irradiation trial (BERT 1.5) conducted in the authors' institution are presented, supporting the use of DVH based on quantitative IVUS measurements for optimal dose prescription in vascular interventional radiation therapy.

37 citations


Journal ArticleDOI
TL;DR: A new design of stent is reported which allows creation of a double-hemispheric lumen for the treatment of a bifurcational stenosis and the unfavourable outcome following the implantation is described.
Abstract: We report a case of implantation of a new design of stent which allows creation of a double-hemispheric lumen for the treatment of a bifurcational stenosis. The unfavourable outcome following the implantation of this stent is described.

1 citations


Journal ArticleDOI
TL;DR: This work describes a novel way of treating a side-branch jailed by a self-expanding stent by using stent implantation through the strut of aSelf-exp expanding stent.
Abstract: Jailing of a side-branch is a known complication of stent implantation, and makes access to the side-branch difficult, especially if the stent is of the self-expanding type. Although plain balloon angioplasty is feasible for the jailed side-branches, the use of newer devices (a stent, Rotablation or atherectomy) has not been described. We describe a novel way of treating a side-branch jailed by a self-expanding stent by using stent implantation through the strut of a self-expanding stent.