M
Manica Negahdaripour
Researcher at Shiraz University of Medical Sciences
Publications - 96
Citations - 2636
Manica Negahdaripour is an academic researcher from Shiraz University of Medical Sciences. The author has contributed to research in topics: Medicine & Epitope. The author has an hindex of 21, co-authored 76 publications receiving 1488 citations. Previous affiliations of Manica Negahdaripour include Shiraz University.
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Exploring 3D structure of human gonadotropin hormone receptor at antagonist state using homology modeling, molecular dynamic simulation, and cross-docking studies
Amirhossein Sakhteman,Minasadat Khoddami,Manica Negahdaripour,Arash Mehdizadeh,Mohsen Tatar,Younes Ghasemi +5 more
TL;DR: The structure of human gonadotropin hormone receptor was subjected to homology modeling studies and molecular dynamic simulation within a DPPC lipid bilayer for 100 ns and a reasonable correlation between docking calculated energy scores and experimental activity values was obtained.
Journal ArticleDOI
Designing a therapeutic and prophylactic candidate vaccine against human papillomavirus through vaccinomics approaches.
Ashkan Bagheri,Navid Nezafat,Mahboobeh Eslami,Younes Ghasemi,Manica Negahdaripour,Manica Negahdaripour +5 more
TL;DR: In this article, a vaccine construct with dual prophylactic and therapeutic applications consisting of several epitope regions on L2, E6, and E7 proteins of HPV16 was designed.
Computational analysis of collagenase from different Vibrio, Clostridium and Bacillus strains to find new enzyme sources
TL;DR: Analysis of 30 collagenases from different species of Clostridium, Vibrio and Bacillus showed that the non-pathogenic C. novyi (NT) with the aliphatic index, instability index, and two PPC domain could be suggested as potent bacteria for industrial production of collagenase.
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Deep analysis of N-cadherin/ADH-1 interaction: a computational survey.
Mahboobeh Eslami,Navid Nezafat,Sahar Khajeh,Zohreh Mostafavi-Pour,Samaneh Bagheri Novir,Manica Negahdaripour,Younes Ghasemi,Vahid Razban +7 more
TL;DR: Quantum mechanics calculations were used to investigate the chemical nature of ADH-1 and indicated that hydrophobic and electrostatic interactions are almost equally involved in the implantation of ADh-1 in the N-cadherin binding site.
Journal ArticleDOI
Production and Preliminary In Vivo Evaluations of a Novel in silico-designed L2-based Potential HPV Vaccine.
Manica Negahdaripour,Navid Nezafat,Reza Heidari,Nasrollah Erfani,Nasim Hajighahramani,Mohammad Bagher Ghoshoon,Eskandar Shoolian,Mohammad Rahbar,Sohrab Najafipour,Ali Dehshahri,Mohammad Hossein Morowvat,Younes Ghasemi +11 more
TL;DR: The obtained cytokine induction profile implied both cellular and humoral responses, with a more Th-1 favored trend, suggests lack of unwanted inflammatory side effects despite using a combination of two TLR agonists.