M
Manisha P. Desai
Researcher at University of Michigan
Publications - 3
Citations - 1842
Manisha P. Desai is an academic researcher from University of Michigan. The author has contributed to research in topics: Microparticle & Toxoid. The author has an hindex of 3, co-authored 3 publications receiving 1756 citations.
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Journal ArticleDOI
Gastrointestinal uptake of biodegradable microparticles: effect of particle size.
TL;DR: There is a microparticle size dependent exclusion phenomena in the gastrointestinal mucosal tissue with 100 nm size particles showing significantly greater tissue uptake, which has important implications in designing of nanoparticle-based oral drug delivery systems, such as an oral vaccine system.
Journal ArticleDOI
The mechanism of uptake of biodegradable microparticles in Caco-2 cells is size dependent.
TL;DR: Caco-2 cells are used as an in vitro model for gastrointestinal uptake, and therefore the results obtained in these studies could be of significant importance in optimizing the microparticle-based oral drug delivery systems.
Journal ArticleDOI
Immune response with biodegradable nanospheres and alum: studies in rabbits using staphylococcal enterotoxin B-toxoid.
TL;DR: It is suggested that biodegradable nanospheres could be used as a vaccine adjuvant after sustained release of the toxoid under in vitro conditions.