M
Manuela Colombo
Researcher at University of Milan
Publications - 8
Citations - 1515
Manuela Colombo is an academic researcher from University of Milan. The author has contributed to research in topics: Blood pressure & Microneurography. The author has an hindex of 8, co-authored 8 publications receiving 1450 citations. Previous affiliations of Manuela Colombo include University of Milano-Bicocca.
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Journal ArticleDOI
Sympathetic activation in obese normotensive subjects
Guido Grassi,Gino Seravalle,Bianca M. Cattaneo,G.B. Bolla,Antonio Lanfranchi,Manuela Colombo,Cristina Giannattasio,Amelia Brunani,Francesco Cavagnini,Giuseppe Mancia +9 more
TL;DR: In this paper, the authors investigated whether these alterations involve sympathetic drive in 10 young obese sub-groups and found that the sympathetic drive was not involved in the majority of the cases.
Journal ArticleDOI
Body weight reduction, sympathetic nerve traffic, and arterial baroreflex in obese normotensive humans
Guido Grassi,Gino Seravalle,Manuela Colombo,Giambattista Bolla,Bianca M. Cattaneo,Francesco Cavagnini,Giuseppe Mancia +6 more
TL;DR: Reduction in body weight induced by a hypocaloric diet with normal sodium content exerts a marked reduction in sympathetic activity owing to central sympathoinhibition, which can be due to the consequences of an increased insulin sensitivity but also to a restoration of the baroreflex control of the cardiovascular system with weight loss.
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Dissociation Between Muscle and Skin Sympathetic Nerve Activity in Essential Hypertension, Obesity, and Congestive Heart Failure
TL;DR: In various diseases, muscle but not skin sympathetic activity is increased, with the sympathetic activation not being uniformly distributed over the whole cardiovascular system, in essential hypertension, obesity, and congestive heart failure.
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Fluctuations of radial artery distensibility throughout the menstrual cycle.
Cristina Giannattasio,Monica Failla,Alessandra Grappiolo,M. L. Stella,Alberto Del Bo,Manuela Colombo,Giuseppe Mancia +6 more
TL;DR: The natural menstrual cycle is characterized by alterations in radial artery distensibility, which is possible to be due to an estrogen-dependent reduction in vascular smooth muscle tone, whereas the arterial stiffening of the luteal phase depends on vascular smooth Muscle contraction due to more complex hormonal phenomena.
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Long-term sympathoinhibitory effects of surgically induced weight loss in severe obese patients
Gino Seravalle,Manuela Colombo,Paolo Perego,Vittorio Giardini,Marco Volpe,Raffaella Dell'Oro,Giuseppe Mancia,Guido Grassi +7 more
TL;DR: Evidence is provided that massive weight loss induced by sleeve gastrectomy triggers profound sympathoinhibitory effects, associated with a stable and significant reduction in plasma leptin levels, whereas the improvement in insulin sensitivity was attenuated with time and unrelated to the sympathoinhibition.