M
Manzar Alam
Researcher at Central University of Jharkhand
Publications - 22
Citations - 351
Manzar Alam is an academic researcher from Central University of Jharkhand. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 4, co-authored 6 publications receiving 78 citations.
Papers
More filters
Journal ArticleDOI
Epigallocatechin 3-gallate: From green tea to cancer therapeutics.
Manzar Alam,Sabeeha Ali,Ghulam Md Ashraf,Anwar L. Bilgrami,Dharmendra Kumar Yadav,Md. Imtaiyaz Hassan +5 more
TL;DR: In this article , the authors highlighted the pharmacological features of EGCG and its therapeutic implications in cancer and other metabolic diseases, focusing on anti-cancer, antioxidant, anti-inflammatory, antiangiogenesis, and apoptotic effects.
Journal ArticleDOI
Therapeutic Implications of Caffeic Acid in Cancer and Neurological Diseases
Manzar Alam,Sarfraz Ahmed,Abdelbaset Mohamed Elasbali,Mohd Adnan,Shoaib Alam,Md. Imtaiyaz Hassan,Visweswara Rao Pasupuleti +6 more
TL;DR: The current review focuses on CA’s chemical, physical, and pharmacological properties, including antioxidant, anti-inflammatory, anticancer, and neuroprotective effects.
Journal ArticleDOI
The elevated activation of NFκB and AP-1 is correlated with differential regulation of Bcl-2 and associated with oral squamous cell carcinoma progression and resistance.
Manzar Alam,Tanushree Kashyap,Kamdeo K. Pramanik,Abhay K. Singh,Siddavaram Nagini,Rajakishore Mishra +5 more
TL;DR: The study provides evidence of increased bcl-2 mRNA/protein fueled by NFĸB in PT and AP-1 in RCRT in overall PT progression and chemoradiation resistance.
Journal ArticleDOI
Glycogen synthase kinase-3β mediated regulation of matrix metalloproteinase-9 and its involvement in oral squamous cell carcinoma progression and invasion
Kamdeo K. Pramanik,Siddavaram Nagini,Abhay K. Singh,Prajna Mishra,Tanushree Kashyap,Nidhi Nath,Manzar Alam,Ajay Rana,Rajakishore Mishra +8 more
TL;DR: The results show that MMP-9 overexpression and activation are important events occurring during OSCC progression/invasion and that this overeexpression/activation is regulated by c-Myc, active M MP-2 and inactive GSK3β mediated pathways.
Journal ArticleDOI
Reversion-inducing cysteine-rich protein with Kazal motifs and its regulation by glycogen synthase kinase 3 signaling in oral cancer.
Kamdeo K. Pramanik,Abhay K. Singh,Manzar Alam,Tanushree Kashyap,Prajna Mishra,Aditya K. Panda,Ratan Kumar Dey,Ajay Rana,Siddavaram Nagini,Rajakishore Mishra +9 more
TL;DR: It is demonstrated that the silencing of the RECK gene, possibly regulated by the GSK3β pathway, is an important event in oral cancer invasion and this pathway could be exploited for therapeutic interventions.