M
Marc Ouellette
Researcher at Laval University
Publications - 205
Citations - 10545
Marc Ouellette is an academic researcher from Laval University. The author has contributed to research in topics: Leishmania infantum & Gene. The author has an hindex of 61, co-authored 200 publications receiving 9789 citations.
Papers
More filters
Journal ArticleDOI
The initial state of the human gut microbiome determines its reshaping by antibiotics
Frédéric Raymond,Amin Ahmed Ouameur,Maxime Déraspe,Naeem Iqbal,Hélène Gingras,Bédis Dridi,Philippe Leprohon,Pier-Luc Plante,Richard Giroux,Ève Bérubé,Johanne Frenette,Dominique K. Boudreau,Jean-Luc Simard,Isabelle Chabot,Marc-Christian Domingo,Sylvie Trottier,Maurice Boissinot,Ann Huletsky,Paul H. Roy,Marc Ouellette,Michel G. Bergeron,Jacques Corbeil +21 more
TL;DR: It is shown that standard antibiotic treatment can alter the gut microbiome in a specific, reproducible and predictable manner, and a subgroup of participants who were enriched in the opportunistic pathogen Enterobacter cloacae after exposure to the antibiotic, an effect linked to lower initial microbiome diversity and to a Bacteroides enterotype is identified.
Patent
Species-specific and universal DNA probes and amplification primers to rapidly detect and identify common bacterial pathogens and associated antibiotic resistance genes from clinical specimens for routine diagnosis in microbiology laboratories
TL;DR: In this article, a method for universal detection of bacteria in biological samples and for specific detection of Escherichia coli, Klebsiella pneumoniae, Enterococcus faecalis, Pseudomonas aeruginosa, Proteus mirabilis, Staphylococcus saprophyticus, Streptococcus pneumoniae and Moraxella catarrhalis in urine or any other biological samples was proposed.
Journal ArticleDOI
Co‐amplification of the γ‐glutamylcysteine synthetase gene gsh1 and of the ABC transporter gene pgpA in arsenite‐resistant Leishmania tarentolae
TL;DR: The results support the previous suggestion that PgpA recognizes metals conjugated to thiols and suggest that at least one more factor acts synergistically with the gsh1 gene product, contributing to resistance.
Journal ArticleDOI
Episomal and stable expression of the luciferase reporter gene for quantifying Leishmania spp. infections in macrophages and in animal models.
Gaétan Roy,Carole Dumas,Denis Sereno,Ying Wu,Ajay K. Singh,Michel J. Tremblay,Marc Ouellette,Martin Olivier,Barbara Papadopoulou +8 more
TL;DR: LUC-expressing recombinant parasites were useful to monitor Leishmania spp.
Journal ArticleDOI
A combined proteomic and transcriptomic approach to the study of stage differentiation in Leishmania infantum
François McNicoll,Jolyne Drummelsmith,Michaela Müller,Eric Madore,Nathalie Boilard,Marc Ouellette,Barbara Papadopoulou +6 more
TL;DR: The results suggest that post‐transcriptional controls at translational and post-translational levels could play major roles in differentiation in Leishmania parasites.