M
Marcel den Dulk
Researcher at Leiden University Medical Center
Publications - 30
Citations - 2193
Marcel den Dulk is an academic researcher from Leiden University Medical Center. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 7, co-authored 7 publications receiving 1757 citations.
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Journal ArticleDOI
Definition and grading of anastomotic leakage following anterior resection of the rectum: a proposal by the International Study Group of Rectal Cancer.
Nuh N. Rahbari,Jürgen Weitz,Werner Hohenberger,Richard J. Heald,Brendan Moran,Alexis Ulrich,Torbjörn Holm,W. Douglas Wong,Emmanuel Tiret,Y. Moriya,Søren Laurberg,Marcel den Dulk,Cornelis J.H. van de Velde,Markus W. Büchler +13 more
TL;DR: The proposed definition and clinical grading of anastomotic leakage is applicable easily in the setting of clinical studies and should be applied in future reports to facilitate valid comparison of the results of different studies.
Journal ArticleDOI
Patients With Curative Resection of cT3-4 Rectal Cancer After Preoperative Radiotherapy or Radiochemotherapy: Does Anybody Benefit From Adjuvant Fluorouracil-Based Chemotherapy? A Trial of the European Organisation for Research and Treatment of Cancer Radiation Oncology Group
Laurence Collette,Jean-François Bosset,Marcel den Dulk,Laurent Mineur,Philippe Maingon,L. Radosevic-Jelic,Marianne Pierart,Gilles Calais +7 more
TL;DR: Exploratory analyses suggest that only good-prognosis patients (ypT0-2) benefit from adjuvant CT, and suggests that the same prognostic factors may drive both tumor sensitivity for the primary treatment and long-term clinical benefit from further adjUvant CT.
Journal ArticleDOI
A multivariate analysis of limiting factors for stoma reversal in patients with rectal cancer entered into the total mesorectal excision (TME) trial: a retrospective study.
Marcel den Dulk,Marije Smit,Koen C.M.J. Peeters,Elma Meershoek-Klein Kranenbarg,Harm J. T. Rutten,Theo Wiggers,Hein Putter,Cornelis J.H. van de Velde +7 more
TL;DR: In this paper, the authors describe stoma policy by using data from the total mesorectal excision (TME) trial in patients with rectal cancer and identify factors that limit stoma reversal.
Journal ArticleDOI
The abdominoperineal resection itself is associated with an adverse outcome: The European experience based on a pooled analysis of five European randomised clinical trials on rectal cancer
Marcel den Dulk,Hein Putter,Laurence Collette,Corrie A.M. Marijnen,Joakim Folkesson,Jean-François Bosset,Claus Rödel,Krzysztof Bujko,Lars Påhlman,Cornelis J.H. van de Velde +9 more
TL;DR: The results suggest that the APR procedure itself is a significant predictor for non-radical resections and increased risk of LR and death due to cancer for patients with advanced rectal cancer.
Journal ArticleDOI
Risk factors for adverse outcome in patients with rectal cancer treated with an abdominoperineal resection in the total mesorectal excision trial
Marcel den Dulk,Corrie A.M. Marijnen,Hein Putter,Harm J. T. Rutten,Geerard L. Beets,Theo Wiggers,Iris D. Nagtegaal,Cornelis J.H. van de Velde +7 more
TL;DR: Age, T-Stage, N-stage, CRM, distance of the tumor to the anal verge, and tumor location were independent risk factors for adverse outcome in patients treated with an APR for low rectal cancer.