C
Claus Rödel
Researcher at Goethe University Frankfurt
Publications - 415
Citations - 26141
Claus Rödel is an academic researcher from Goethe University Frankfurt. The author has contributed to research in topics: Chemoradiotherapy & Radiation therapy. The author has an hindex of 62, co-authored 368 publications receiving 22592 citations. Previous affiliations of Claus Rödel include University of Erlangen-Nuremberg & German Cancer Research Center.
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Journal ArticleDOI
Preoperative versus Postoperative Chemoradiotherapy for Rectal Cancer
Rolf Sauer,Heinz Becker,Werner Hohenberger,Claus Rödel,Christian Wittekind,Rainer Fietkau,Peter Martus,Jörg Tschmelitsch,Eva Hager,Clemens F. Hess,Torsten Liersch,Heinz Schmidberger,Rudolf Raab +12 more
TL;DR: Preoperative chemoradiotherapy, as compared with postoperative cheMoradi therapy, improved local control and was associated with reduced toxicity but did not improve overall survival.
Journal ArticleDOI
Preoperative Versus Postoperative Chemoradiotherapy for Locally Advanced Rectal Cancer: Results of the German CAO/ARO/AIO-94 Randomized Phase III Trial After a Median Follow-Up of 11 Years
Rolf Sauer,Torsten Liersch,Susanne Merkel,Rainer Fietkau,Werner Hohenberger,Clemens F. Hess,Heinz Becker,Hans-Rudolf Raab,Marie-Therese Villanueva,Helmut Witzigmann,Christian Wittekind,Tim Beissbarth,Claus Rödel +12 more
TL;DR: In this paper, the authors reported long-term results with a median follow-up of 134 months, where they found a difference of 10% in 5-year overall survival as the primary end point.
Journal ArticleDOI
Long-term outcome in patients with a pathological complete response after chemoradiation for rectal cancer: a pooled analysis of individual patient data
Monique Maas,Patty J. Nelemans,Vincenzo Valentini,Prajnan Das,Claus Rödel,Li Jen Kuo,Felipe A. Calvo,Julio Garcia-Aguilar,Rob Glynne-Jones,Karin Haustermans,Mohammed Mohiuddin,Salvatore Pucciarelli,William Small,Javier Suárez,George Theodoropoulos,Sebastiano Biondo,Sebastiano Biondo,Regina G. H. Beets-Tan,Geerard L. Beets +18 more
TL;DR: Patients with pCR after chemoradiation have better long-term outcome than do those without pCR, and pCR might be indicative of a prognostically favourable biological tumour profile with less propensity for local or distant recurrence and improved survival.
Journal ArticleDOI
Prognostic Significance of Tumor Regression After Preoperative Chemoradiotherapy for Rectal Cancer
Claus Rödel,Peter Martus,Thomas Papadoupolos,László Füzesi,Martin Klimpfinger,Rainer Fietkau,Torsten Liersch,Werner Hohenberger,Rudolf Raab,Rolf Sauer,Christian Wittekind +10 more
TL;DR: In this exploratory analysis, complete ( TRG 4) and intermediate pathologic response (TRG 2 + 3) suggested improved DFS after preoperative CRT, and TRG assessment should be implemented in pathologic evaluation and prospectively validated in further studies.
Journal ArticleDOI
Simultaneous radiochemotherapy versus radiotherapy alone in advanced head and neck cancer: a randomized multicenter study.
Wendt Tg,Gerhard G. Grabenbauer,Claus Rödel,H J Thiel,H Aydin,R Rohloff,T P Wustrow,Heinrich Iro,C Popella,A Schalhorn +9 more
TL;DR: Concomitant CT offered improved disease control and survival in advanced head and neck cancer patients due to increased acute toxicity, more supportive care is demanded when CT is given simultaneously.